Pederson suffered an upper-body injury Sunday against the Islanders and will not return to the game.
Pederson is competing for a spot on Philadelphia's roster, so this injury could hurt his chances of making the team if he's sidelined for a large chunk of time. The 28-year-old last appeared in the NHL in 2022-23, suiting up in 27 regular-season games between the Blue Jackets and Canucks.