Getty Images

Accomplished Slovenian cyclist and three-time Tour de France winner Tadej Pogacar looks to win back-to-back titles when he competes in the 2025 Tour de France starting on Saturday. Pogacar also won back-to-back titles in the three-week event in 2020 and 2021. Pogacar, 26, has won 17 individual stages at the Tour de France over the past five years. Besides his three General classification wins, he won the Mountains classification in 2020 and 2021, and Young rider classification in 202, 2021, 2022 and 2023.

Pogacar enters as the odds-on favorite at -290, followed by Jonas Vingegaard (+250), Remco Evenepoel (+1000) and Joao Almeida (+1800) in the latest 2025 Tour de France odds. The event begins on Saturday at 7:10 a.m. ET and runs through July 27. Before making any 2025 Tour de France picks or predictions, you need to see what cycling insider and SportsLine senior writer Gene Menez has to say.

A former reporter and associate editor for Sports Illustrated, where he covered an array of sports for almost 14 years, Menez has been following the iconic three-week race since the mid-1980s when Greg LeMond was riding to three yellow jerseys. Menez correctly hit Adam Yates to finish in the top three overall in 2023, at +3300. 

Now, Menez has scrutinized the latest Tour de France 2025 odds and released his coveted best bets. He's sharing all his picks and analysis at SportsLine. And if you're a new user, be sure to see the latest FanDuel promo code, DraftKings promo code and BetMGM promo code to get even more value.

Top 2025 Tour de France predictions

For the 2025 Tour de France, Menez is high on Joao Almeida to earn a podium finish, a bet that returns +250.

"The 26-year-old from Portugal will once again enter the Tour de France in a supporting role for UAE Team Emirates-XRG teammate Tadej Pogacar," Menez told SportsLine. "But that did not stop Almeida from finishing fourth in the Tour last year. This year he enters the Tour in much better form; he already has won the Tours of the Basque Country, Romandie and Switzerland.

If Pogacar and Jonas Vingegaard finish one-two as expected, Almeida's biggest competition for a podium spot figures to be Remco Evenepoel, but Almeida already has beaten that rival this year, at Romandie." See what other Tour de France picks Menez likes at SportsLine.

How to make 2025 Tour de France picks 

Menez has locked in two other best bets for this race, including one prop that pays more than +800. You can only see what they are here.

So who wins the 2025 Tour de France and which cyclists should you back? Visit SportsLine now to see the 2025 Tour de France picks and best bets from a cycling insider, and find out.

2025 Tour de France odds, top contenders

See Tour de France picks at SportsLine

(odds subject to change)
(Top 20 cyclists odds to win)
Tadej Pogacar -290
Jonas Vingegaard +250
Remco Evenepoel +1000
Joao Almeida +1800
Primoz Roglic +2800
Florian Lipowitz +3000
Matteo Jorgenson +4000
Felix Gall +10000
Simon Yates +10000
Mattias Skjelmose +12000
Enric Mas Nicolau +15000
Carlos Rodriguez +15000
Ben O'Connor +15000
Tobias Halland Johannessen +15000
Sepp Kuss +15000
Lenny Martinez +20000
Alexander Vlasov +20000
Adam Yates +20000
Santiago Buitrago +20000
Oscar Onley +30000