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The 2021 Wyndham Championship is the final PGA Tour event before the start of the FedEx Cup Playoffs, so a talented field has descended upon Sedgefield Country Club in Greensboro, North Carolina. A number of players need a good performance in order to rack up some late FedEx Cup points to make a postseason push. Hideki Matsuyama won the 2021 Masters and he's one of the biggest names in the 2021 Wyndham Championship field. Matsuyama is currently 14th in the FedEx Cup standings and could theoretically surge to as high as third with a victory.

The latest 2021 Wyndham Championship odds from Caesars Sportsbook list Matsuyama at 14-1. Webb Simpson, the 2011 champion of this event, is going off as the 12-1 favorite on the PGA odds board. Other Wyndham Championship 2021 contenders include Louis Oosthuizen (18-1) and Patrick Reed (22-1). Before locking in your 2021 Wyndham Championship picks, be sure to see the golf predictions and projected leaderboard from the proven computer model at SportsLine.

SportsLine's proprietary model, built by DFS pro Mike McClure, has been red-hot since the PGA Tour resumed last June. In fact, it's up almost $10,500 on its best bets since the restart, nailing tournament after tournament.

At the 2021 Open Championship, McClure's best bets included Collin Morikawa winning outright even though he was listed as a massive 40-1 long shot. He was also all over Daniel Berger (+220) and Emiliano Grillo (+700) finishing inside the top-20. McClure's best bets netted over $2,200 at the 2021 Open Championship.

In addition, McClure's model was all over Jon Rahm's (10-1) first career major championship victory at the 2021 U.S. Open. Rahm was two strokes off the lead heading into the weekend, but the model still projected him as the winner. And at the 2021 Masters, McClure nailed Rahm's (+250) top-five finish in his best bets, as well as Corey Conners' (+550) top-10 showing.  

This same model has also nailed a whopping seven majors entering the weekend. Anyone who has followed it has seen massive returns.

Now that the 2021 Wyndham Championship field is locked, SportsLine simulated the event 10,000 times, and the results were surprising. Head to SportsLine now to see the projected 2021 Wyndham Championship leaderboard.

The model's top 2021 Wyndham Championship predictions 

One major surprise the model is calling for at the 2021 Wyndham Championship: Matsuyama, the defending Masters champion and one of the top favorites at 14-1, barely cracks the top five. Matsuyama has had a sensational season thus far, winning his first major championship at Augusta National and securing a runner-up finish last week at the WGC-FedEx St. Jude Invitational. 

However, Matsuyama has struggled at the Wyndham Championship throughout his career. In fact, Matsuyama has missed the cut at this event in three of his last five starts. In addition, Matsuyama has been ice-cold with his putter, entering this week's event ranked 112th in one-putt percentage (39.52), 172nd in total putting (308.2) and 180th in strokes gained: putting. He's not a strong pick to win it all and there are far better values for 2021 Wyndham Championship bets. 

Another surprise: Gary Woodland, a 40-1 long shot, makes a strong run at the title. Woodland has a much better chance to win it all than his odds imply, so he's a target for anyone looking for a huge payday. The 2019 U.S. Open winner hasn't had a great season and needs points to ensure that he'll be around for the 2021 FedEx Cup Playoffs. 

Woodland is currently 108th in the standings with only 125 players being invited to the Northern Trust next week, so he'll inevitably want to make sure he's inside that cutoff and surge into the top 70 to try to earn his way to the BMW Championship two weeks later. That should serve as plenty of motivation for an undoubtedly skilled player. 

In addition, the four-time PGA Tour champion is coming off a top-10 finish last week at the Barracuda Championship, and he's finished inside the top-15 in four of his last nine starts on the PGA Tour. If he's striking the ball well this week, he'll have a great shot at finishing on top of the leaderboard at the 2021 Wyndham Championship.

How to make 2021 Wyndham Championship picks

The model is targeting five other golfers with 2021 Wyndham Championship odds of 28-1 or higher to make a strong run at the title, including a massive long shot higher than 70-1 that would net any bettor an epic payday. Anyone who backs these underdogs could hit it big. You can only see them here.

So who will win the Wyndham Championship 2021? And which long shots stun the golfing world? Check out the odds below and then visit SportsLine to see the projected 2021 Wyndham Championship leaderboard, all from the model that's nailed seven golf majors and is up almost $10,500 since the restart.

2021 Wyndham Championship odds

Webb Simpson 12-1
Hideki Matsuyama 14-1
Louis Oosthuizen 18-1
Patrick Reed 22-1
Brian Harman 28-1
Will Zalatoris 28-1
Jason Kokrak 28-1
Sungjae Im 30-1
Kevin Kisner 33-1
Tommy Fleetwood 33-1
Charl Schwartzel 33-1
Russell Henley 35-1
Matthew Wolff 40-1
Kevin Streelman 40-1
Seamus Power 40-1
Kevin Na 40-1
Si-Woo Kim 40-1
Gary Woodland 40-1
Bubba Watson 40-1
Adam Scott 40-1
Rickie Fowler 45-1
Justin Rose 45-1
Robert Macintyre 45-1
Brandt Snedeker 45-1
Sebastian Munoz 50-1
Branden Grace 50-1
Jhonattan Vegas 50-1
J.T. Poston 50-1
Erik Van Rooyen 50-1
Mito Pereira 50-1
Zach Johnson 55-1
Talor Gooch 55-1
Ryan Moore 60-1
Harold Varner 60-1
Patton Kizzire 66-1
Lucas Glover 66-1
Chez Reavie 66-1
Doug Ghim 66-1
Hank Lebioda 66-1
MacKenzie Hughes 70-1
Ryan Armour 80-1
Luke List 80-1
Doc Redman 80-1
Brendon Todd 80-1
Chris Kirk 80-1
Lanto Griffin 80-1
Rory Sabbatini 80-1
Adam Schenk 80-1
C.T. Pan 80-1
Joel Dahmen 80-1
Keith Mitchell 100-1
Patrick Rodgers 100-1
Kramer Hickok 100-1
Kyle Stanley 100-1
Adam Hadwin 100-1
Matt Jones 100-1
Jim Herman 100-1
Mark Hubbard 100-1
Dylan Frittelli 100-1
Andrew Putnam 100-1
Bo Hoag 100-1
Roger Sloan 100-1
Scott Piercy 100-1
Francesco Molinari 100-1
Tom Lewis 100-1
Brandon Hagy 100-1
Henrik Norlander 125-1
Adam Long 125-1
Scott Stallings 125-1
Matt Kuchar 125-1
Kyoung-Hoon Lee 125-1
Michael Thompson 125-1
Sepp Straka 125-1
Brian Stuard 125-1
Aaron Wise 125-1
Sam Ryder 150-1
Byeong Hun An 150-1
Brice Garnett 150-1
Richy Werenski 150-1
Martin Laird 150-1
Joseph Bramlett 150-1
Jason Dufner 200-1
Camilo Villegas 200-1
Matthew NeSmith 200-1
Nick Taylor 200-1
Wyndham Clark 200-1
Vincent Whaley 200-1
James Hahn 200-1
Russell Knox 200-1
Beau Hossler 200-1
Anirban Lahiri 200-1
Satoshi Kodaira 200-1
Harry Higgs 250-1
Denny McCarthy 250-1
Nate Lashley 250-1
Will Gordon 250-1
Tom Hoge 250-1
Sean O'Hair 250-1
Chesson Hadley 250-1
Bo Van Pelt 250-1
Akshay Bhatia 250-1
Kevin Tway 250-1
Scott Brown 250-1
Chase Seiffert 300-1
Kiradech Aphibarnrat 300-1
Davis Thompson 300-1
Aaron Baddeley 300-1
Mark Anderson 300-1
Alex Smalley 300-1
Vaughn Taylor 300-1
Hudson Swafford 300-1
John Augenstein 300-1
Austin Cook 300-1
J.J. Spaun 300-1
Robby Shelton 300-1
Padraig Harrington 300-1
Tyler Duncan 300-1
Nick Watney 300-1
Cameron Percy 300-1