Few players in the 2021 Wells Fargo Championship field have enjoyed playing the Quail Hollow Club more than Justin Thomas. The No. 2 player in the world, Thomas won the 2017 PGA Championship on this course, which is his only major victory. He also has a top-10 finish back at the 2015 Wells Fargo Championship, so he's one of the safest PGA DFS picks this weekend. But with 15 other major championship winners as part of the field, the PGA DFS player pool is brimming with top talent for the Wells Fargo Championship 2021.

Thomas is listed at $11,300 on DraftKings and $12,300 on FanDuel, so slotting him into your PGA DFS lineups means you'll need to find more economical options elsewhere. Should Thomas be part of your PGA DFS strategy, or will he be unable to replicate his previous success at Quail Hollow Club? Before entering any PGA DFS tournaments or cash games for the 2021 Wells Fargo Championship, you'll want to see the top PGA DFS picks and daily fantasy golf advice from SportsLine's Mike McClure.

McClure is a DFS pro with nearly $2 million in career winnings, and he's been red-hot on his PGA Tour picks this season. McClure is also a predictive data engineer at SportsLine who uses a powerful prediction model that simulates every tournament 10,000 times, taking factors like statistical trends, past results and current form into account. This allows him to find the best PGA DFS values and create optimal lineups that he shares only over at SportsLine. They're a must-see for any PGA DFS player.

In addition, McClure's model is up almost $10,000 on its best bets since the restart, nailing tournament after tournament. This is the same model that has nailed a whopping six majors entering the weekend. Anyone who has followed it has seen massive returns.

Now, McClure has set his sights on the 2021 Wells Fargo Championship and revealed his optimal PGA DFS advice, strategy and player pool. Head to SportsLine now to see his top daily fantasy golf picks for the 2021 Wells Fargo Championship.

Top 2021 Wells Fargo Championship PGA DFS picks

One of McClure's top PGA DFS picks for the Wells Fargo Championship 2021: Patrick Reed at $9,300 on DraftKings and $10,900 on FanDuel. Reed is the No. 7 golfer in the world and knows Quail Hollow Club well as he's played the course seven times in his career. His best finish came when the course hosted the 2017 PGA Championship and Reed finished as runner-up to winner Justin Thomas.

Reed has one victory and three other top-10 finishes on tour this season, including a T-8 finish at the 2021 Masters. He has long been one of the best at putting on tour, but he may be the best this season as he ranks third in strokes gained via putting. He leads the PGA Tour in putting average (1.673), one-putt percentage (45.91) and putts per round (27.71), all of which will be needed at Quail Hollow Club. The course has undergone numerous renovations over the years, but the sloping, firm greens remain, which plays into Reed's strengths.

McClure's optimal PGA DFS strategy also includes rostering Doc Redman at $6,900 on DraftKings and $8,200 on FanDuel. The North Carolina native will be playing not too far from where he grew up in Raleigh. He competed at Quail Hollow Club once before and scored a top-20 finish at the 2019 Wells Fargo Championship.

Redman is one of those players who can do serious damage if he gets on a roll. Earlier this season he carded birdies on six consecutive holes at the 2020 Safeway Open. No golfer has a longer streak than that on tour this season, and it helped propel Redman to a top-three finish at the tournament. Redman is a streaky player but his prices are too good to pass up on for your 2021 Wells Fargo Championship DFS picks.

How to set 2021 Wells Fargo Championship PGA DFS lineups

McClure is also targeting an undervalued player who's primed to play extremely well this week, giving you a huge return on sites like DraftKings and FanDuel. Picks like these could be the difference between winning your PGA DFS contests or going home with nothing. You can only see who it is here.

So what are the top PGA DFS picks for the 2021 Wells Fargo Championship? And which undervalued golfer is a must-roster? Visit SportsLine now to see the complete player pool for FanDuel and DraftKings, all from the expert who's made nearly $2 million in daily fantasy sports, to find out.