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The American League's two best teams since 2017 collide on Friday when the Houston Astros and New York Yankees open a three-game series at Minute Maid Park in Houston. Since the start of the '17 season, the Astros have the best regular season record (394-240) in the AL, and the Yankees have the second best (371-261). Only the Dodgers (399-236) have a better record over that time. First pitch on Friday is 7:05 p.m. ET. The Astros are -140 money-line favorites (risk $140 to win $100) in the latest MLB odds from William Hill Sportsbook, while the Yankees are +130 underdogs. 

The game is one of 15 on Friday's MLB schedule. Other matchups include NL Central-leading Milwaukee hosting second place Cincinnati and the Cubs' Kyle Hendricks looking to beat the Cardinals for his major league-leading 11th victory. Before making any MLB picks or predictions for Friday night, you need to see what the SportsLine Projection Model has to say.

This model, which simulates every pitch of every game 10,000 times, had a banner 2019 season, the league's last full schedule, returning more than $1,400 on its top-rated money-line and run-line MLB picks. It is off to a sizzling start in 2021, going 113-87 on top-rated MLB money-line picks through 14 weeks, returning almost $900. Anyone following it has seen huge rewards.

Now, the model has crunched the numbers for the Friday MLB schedule and posted its best bets. Successfully parlaying these four MLB picks today will pay nearly 18-1. Head to SportsLine now to see the picks

Top MLB picks for Friday, July 9

The model simulated every game 10,000 times and is taking Miami (+120) to take care of Atlanta (7:10 p.m. ET) in the first game of the teams' three-game series at LoanDepot Park in Miami. The Marlins are 6-4 against the Braves this season and have won two of the three series played between the teams. Miami enters the series on a roll, having won three of four games against the Dodgers.

The Marlins have had success this season against the Braves' starter on Friday, Charlie Morton. Miami has scored 13 runs on 16 hits (and eight walks) in three games against Morton this year. The Marlins have a .780 OPS and a .281 batting average against the veteran righty and have won two of the three games he has started.

Featured Game | Miami Marlins vs. Atlanta Braves

How to make MLB predictions, parlays for Friday July 9

The model has locked in three other Friday MLB best bets, including a play on an even bigger underdog. You can see its best bets only at SportsLine.

So which MLB picks should you make on Friday for a shot at a return of almost 18-1? And which underdog do you need to be all over? Visit SportsLine now to see Friday's MLB picks, all from the projection model that is off to a fast start in 2021, and find out.