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Robert Hanashiro / USA TODAY Sports

The Milwaukee Brewers visit Wrigley Field on Friday afternoon to open a three-game NL Central series against the Chicago Cubs. The Brewers (11-7) are in first place in the division, while the Cubs (9-9) are trying to get pointed in the right direction. Right-hander Kyle Hendricks is expected to get the start for Chicago, which finished a sweep of a home series against the Mets with a 4-3 win in 10 innings on Thursday night. Milwaukee is expected to counter with southpaw Brett Anderson after closing out a three-game sweep of the Padres on Wednesday night.  

First pitch is scheduled for 2:20 p.m. ET. The Cubs are the -145 favorite on the money line in the latest Brewers vs. Cubs odds from William Hill Sportsbook, while the over-under for total runs scored is 9.5. Before locking in your Cubs vs. Brewers picks, check out the MLB predictions and betting advice from the SportsLine Projection Model.

This model, which simulates every pitch of every game 10,000 times, had a banner 2019 season, the league's last full schedule, returning more than $1,400 on its top-rated money-line and run-line MLB picks. It is off to a profitable start in 2021, going 21-14 on top-rated MLB money-line picks through three weeks, returning almost $300. Anyone following it has seen huge rewards. 

Now, the model has dialed in on Brewers vs. Cubs. You can visit SportsLine now to see the picks. Here are the MLB lines and trends for Cubs vs. Brewers:

  • Brewers vs. Cubs money line: Milwaukee +135, Chicago -145  
  • Brewers vs. Cubs run line: Chicago -1.5
  • Brewers vs. Cubs over-under: 9.5 runs
  • MIL: Milwaukee is 5-1 in the last six meetings in Chicago
  • CHC: Chicago is 4-0 in its last four games against a left-handed starter
Featured Game | Chicago Cubs vs. Milwaukee Brewers

Why you should back the Brewers

Milwaukee is 7-2 on the road this season and has won seven of its past 10 after a 4-4 start. The Brewers outscored San Diego 13-3 in the three-game set, and they have allowed more than two runs just twice in the past seven games. Anderson is 2-1 with a 2.65 ERA, allowing five earned runs and just four walks over his 17 innings, and the offense has backed him with 19 runs in the three starts.      

The Brewers have scored at least five runs in six of their last 10 games, and they face a pitcher in Hendricks who is 0-2 with a 6.92 ERA and has allowed five home runs over his two starts. Catcher Omar Narvaez has come alive at the plate to complement his stellar defense and pitch framing, hitting .396 (fourth in MLB) with three homers and 10 RBIs. Outfielder Avisail Garcia and third baseman Travis Shaw also have three homers to help carry the offense with Christian Yelich injured. Shaw is tied for eighth in the majors with 15 RBIs and has three doubles.     

Why you should back the Cubs

Seven of Chicago's nine wins have come at Wrigley, and the Cubs tagged Anderson for three home runs in a 5-3 win on home turf in April. Hendricks has allowed just four runs over his last four starts against the Brewers, going 1-0 with 27 strikeouts and three walks. He doesn't throw hard, but he consistently minimizes damage, and his elite changeup can baffle hitters. He faces a Milwaukee team that ranks 30th in the majors with a .209 team batting average, is 27th in slugging percentage (.364) and has the second-most strikeouts in the league (198). 

Chicago's offense still has pop, with Javier BaezKris Bryant and Willson Contreras each putting up five home runs. Contreras, Baez and David Bote all homered off Anderson in the win earlier this month. Baez has a team-high 16 RBIs (tied for fourth in MLB), while Bryant, Bote and Contreras have combined for 32. Baez also can get into scoring position on the base paths and is tied for second in MLB with five of the team's 11 steals. The Cubs have scored 36 runs over their last five games.    

How to make Cubs vs. Brewers picks

SportsLine's model is leaning under on the total, as the teams combine for 8.7 runs in the simulations, and it also says one side of the money line has all the value. You can only see the pick at SportsLine

So who wins Brewers vs. Cubs? And which side of the money line has all the value? Visit SportsLine now to see which side of the money line to jump on, all from the advanced model that returned more than $1,400 in 2019.