The Chicago Cubs (41-59) travel to Oracle Park and take on the San Francisco Giants (50-51) on Sunday Night Baseball. The Cubs have been playing well in the second half thus far, logging a 6-2 record post-All-Star break. Meanwhile, the Giants have been the opposite as they are 2-9 over the past 11 games. All-Star Carlos Rodon (8-6, 3.18) will start for San Francisco with rookie Adrian Sampson (0-1, 3.20) going for Chicago.

The first pitch is set for 7:08 p.m. ET from San Francisco. The Giants are the -190 money line favorite (risk $190 to win $100) in the latest Cubs vs. Giants odds from Caesars Sportsbook, while the Cubs are a +158 underdog. The over-under for total runs scored is 7.5. Before making any Giants vs. Cubs picks, you need to see the MLB predictions and betting advice from SportsLine's advanced computer simulation model.

The SportsLine Projection Model simulates every MLB game 10,000 times, and it is 284-243 on top-rated MLB money-line picks since the start of the 2021 season, returning over $400 for $100 players. This is the same model that pegged the 2021 Atlanta Braves at 10-1 as one of three best bets to win it all last season. Anybody who has followed it has seen profitable returns.

Now, the model has set its sights on Cubs vs. Giants and just locked in its picks and MLB predictions. You can head to SportsLine now to see the model's picks. Now, here are several MLB odds and betting lines for Giants vs. Cubs:

  • Cubs vs. Giants money line: San Francisco -190, Chicago +158
  • Cubs vs. Giants run-line: Chicago +1.5 (-135)
  • Cubs vs. Giants over-under: 7.5 runs
  • CHC: Cubs are 4-1 in their last five road games
  • SF: Giants are 5-1 in their last six vs. National League Central
  • Cubs vs. Giants picks: See picks at SportsLine
Featured Game | San Francisco Giants vs. Chicago Cubs

Why you should back the Giants

The southpaw Rodon will be taking the mound in this primetime affair and he will be confident on the hill due to his abundance of dominant pitches. The two-time All-Star owns a blazing fastball to accompany a nasty slider and curveball in his repertoire. Rodon is second in the NL in both strikeouts (148) and strikeouts per nine IP (11.5). He's recorded 10-plus strikeouts in two of his last four starts.

First baseman Brandon Belt has been an offensive option in the middle of the lineup with home-run and gap-producing power. After hitting just .172 in June, Belt's average is at .271 in July and he's reached base safely nine times over his last five games. He's also taken advantage of RHPs like Sampson as 13 of Belt's 15 extra-base hits have come against righties.

Why you should back the Cubs

Shortstop Nico Hoerner is an exceptional hitter with an outstanding ability to make contact. Hoerner's swing is compact and he's showcased defensive grit as one of the top fielding shortstops in the game. At the plate, Hoerner leads the team in batting average (.297) with six home runs and 33 RBI. On July 26, he went 2-for-4 with a double and one RBI.

Catcher Willson Contreras has been a calm offensive option for the Cubs. Contreras displays home-run power and run-producing abilities while still being a stout defender. The three-time All-Star is second on the club in home runs (14) with 38 runs driven in. Additionally, he's leading the team in OBP (.369) and went 2-for-5 in his last outing.

How to make Cubs vs. Giants picks

SportsLine's model is leaning over on the total, projecting 8.4 combined runs. It also says one side of the money line has all the value. You can only get the model's MLB picks at SportsLine.

So who wins Giants vs. Cubs? And which side has all the value? Visit SportsLine now to see which side you need to jump on, all from the model that has crushed its MLB picks, and find out.