Cubs vs. Mariners odds, line, prediction, start time: 2025 MLB picks, June 20 best bets from proven model
SportsLine's model simulated the Seattle Mariners vs. Chicago Cubs 10,000 times and revealed its MLB picks for Friday's matchup
By
Daniel Kohn
•
3 min read
The Seattle Mariners will meet the Chicago Cubs in a key interleague matchup on Friday afternoon. Seattle is coming off a 3-1 loss to the Boston Red Sox on Wednesday, while Chicago dropped an 8-7 decision to Milwaukee on Thursday. The Mariners (37-36), who have lost two of three, are 17-17 on the road in 2025. The Cubs (45-29), who have won three of four, are 24-13 on their home field this season.
First pitch from Wrigley Field in Chicago is set for 2:20 p.m. ET. The Cubs have won eight of the past 10 meetings with the Mariners. Chicago is a -147 favorite on the money line (risk $147 to win $100) in the latest Mariners vs. Cubs odds from FanDuel Sportsbook, while the total number of runs Vegas thinks will be scored, or the over/under, is 9.5. Before making any Cubs vs. Mariners picks, be sure to see the MLB predictions and betting advice from SportsLine's proven computer model.
The SportsLine Projection Model simulates every MLB game 10,000 times. It enters Week 13 of the 2025 MLB season on a 37-30 run on top-rated MLB sides picks. It has excelled in making home run prop picks, returning more than 35 units of profit over the past two months. Anybody following at sportsbooks and on betting apps could have seen strong returns.
Now, the model has set its sights on Mariners vs. Cubs and just locked in its picks and MLB predictions. You can head to SportsLine now to see the model's picks. Here are several MLB odds and betting lines for Cubs vs. Mariners, which you can get in on with a DraftKings promo code or a FanDuel promo code.
Mariners vs. Cubs money line | Seattle +123, Chicago -147 at FanDuel Sportsbook |
Mariners vs. Cubs over/under | 9.5 runs |
Mariners vs. Cubs run line | Chicago -1.5 (+142) |
Mariners vs. Cubs picks | |
Mariners vs. Cubs streaming | Fubo (Try for free) |
Why the Cubs can win
Left-hander Matthew Boyd (6-3, 2.79) will take the mound for Chicago. He's been exceptional in June for the Cubs, giving up just four earned runs in 19.1 innings pitched. He picked up the win last time out, going six innings against the Pirates and giving up just one earned run.
Right fielder Kyle Tucker has been red hot. He was 3-for-4 with two doubles and one run scored in Tuesday's 5-3 win over the Milwaukee Brewers. He was 2-for-4 in a 2-1 win over the Pittsburgh Pirates on Saturday. In 73 games this season, he is batting .279 with 15 doubles, four triples, 13 homers, 43 RBI and 18 stolen bases. See which team to back at SportsLine.
Why the Mariners can win
Right-hander George Kirby (1-3, 5.96 ERA) will start for Seattle. He is coming off a solid effort in a 4-3 win over the Cleveland Guardians on Saturday. Although he received a no-decision, he pitched five innings, allowing five hits, two earned runs and three walks with five strikeouts. He picked up a win in a 3-2 victory over the Los Angeles Angels on June 8, pitching seven innings and allowing two hits, two earned runs and no walks with 14 strikeouts.
Offensively, catcher Cal Raleigh is among Seattle's top hitters. In 72 games this season, he is batting .266 with 14 doubles, 27 home runs, 60 RBI and eight stolen bases. In an 8-0 win over the Boston Red Sox on Tuesday, he was 3-for-4 with a double, home run and six RBI. He also doubled in Wednesday's loss to Boston. He has hits in seven of the last 10 games. See which team to back at SportsLine.
How to make Mariners vs. Cubs picks
SportsLine's model is leaning Under on the total, projecting 8.4 combined runs, and it says one side of the money line has all the value. You can head to SportsLine to see the model's MLB picks.
So who wins Cubs vs. Mariners, and which side of the money line has all the value? Visit SportsLine now to see which side you need to jump on, all from the model that has crushed its MLB picks, and find out.
