An intriguing interleague game gets the Tuesday MLB schedule underway when the Baltimore Orioles host the Chicago Cubs. Baltimore has surged atop the AL East standings at 57-33, passing the slumping Yankees. Chicago is 5.5 games out of the final NL wild-card spot, though five teams stand in the way. Jameson Taillon (5-4, 2.99 ERA) is the projected stater for Chicago. Dean Kremer (4-4, 3.93 ERA) is on the hill for Baltimore. 

First pitch is 6:35 p.m. ET at Oriole Park at Camden Yards. The latest Cubs vs. Orioles odds via SportsLine consensus list Baltimore as the -154 favorite (risk $154 to win $100). The over/under is 9. Before making any Orioles vs. Cubs picks, be sure to check out the MLB predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every MLB game 10,000 times. It entered Week 16 of the 2024 MLB season a profitable 49-37 on all-top rated MLB picks this season. Dating back to last season, it is on a 24-9 roll on top-rated run-line picks (+1077). Anybody following has seen strong returns. 

Now, the model has set its sights on Orioles vs. Cubs and just locked in its picks and MLB predictions. You can head to SportsLine now to see the model's picks. Now, here are several MLB odds and betting lines for Cubs vs. Orioles:

  • Orioles vs. Cubs money line: Orioles -154, Cubs +129
  • Orioles vs. Cubs run line: Orioles -1.5 (+130) 
  • Orioles vs. Cubs over/under: 9 runs
  • Orioles vs. Cubs picks: See picks at SportsLine

Top Cubs vs. Orioles pick

For Orioles vs. Cubs, one of the top picks from SportsLine's model is that Orioles outfielder Cedric Mullins goes Over 0.5 total bases (-175). The model is projecting 1.5 total bases for him and rates this pick as the maximum five stars in confidence. 

Mullins had an up-and-down road trip, alternating games with and without at least one hit. However, the model has spotted an edge for Mullins as he takes on Taillon, a pitcher he has dominated. Mullins has a .417 batting average and a sizzling 1.450 OPS against him, dating back to their time as AL East rivals when Taillon pitched for the Yankees. 

Mullins also has better splits both at home and against righties, which is what Taillon is, so the model is confident that he'll get at least a single in this one to hit this prop. See more picks at SportsLine

How to make Orioles vs. Cubs picks

In addition to that prop pick, the model also says one side of the money line has all the value. You can only get the MLB model's picks and analysis at SportsLine.

So who wins Cubs vs. Orioles, and which side of the money line has all the value? Visit SportsLine now to see which side you need to jump on, all from the model that's 49-37 on top-rated MLB picks, and find out.