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Game 5 of the 2024 NLDS has the Los Angeles Dodgers hosting the San Diego Padres. A trip to the NLCS against the New York Mets is on the line. This series has gone back and forth but the Dodgers evened things up 2-2 on Wednesday. Los Angeles beat the Padres 8-0 to secure the win. Yu Darvish (7-3, 3.31 ERA) is on the hill for San Diego. Yoshinobu Yamamoto (7-2, 3.00 ERA) will get the start for Los Angeles. Freddie Freeman, who has been battling an ankle injury this series and didn't play in Game 4, is in the lineup and hitting third for Los Angeles behind Shohei Ohtani and Mookie Betts. 

First pitch from Dodger Stadium in Los Angeles is set for 8:08 p.m. ET. Los Angeles is a -144 favorite on the money line (risk $144 to win $100) in the latest Padres vs. Dodgers odds from SportsLine consensus, while the total number of runs Vegas thinks will be scored, or the over/under, is 8. Before making any Dodgers vs. Padres picks, be sure to see the MLB predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every MLB game 10,000 times. Entering the second week of the 2024 MLB playoffs, it's on a 32-17 roll on top-rated run-line picks (+822) that dates back to last season. Anybody following has seen strong returns. 

Now, the model has set its sights on Padres vs. Dodgers and just locked in its picks and MLB predictions. You can head to SportsLine now to see the model's picks. Now, here are several MLB odds and betting lines for Dodgers vs. Padres: 

  • Dodgers vs. Padres money line: Los Angeles -144, San Diego +122
  • Dodgers vs. Padres over/under: 8 runs
  • Dodgers vs. Padres run line: Los Angeles -1.5 (+144)
  • LAD: The Los Angeles Dodgers have hit the team total Over in 21 of their last 35 games at home
  • SD: The San Diego Padres have covered the run line in 50 of their last 83 away games
  • Dodgers vs. Padres picks: See picks at SportsLine
  • Dodgers vs. Padres streaming: FuboTV (Try for free)

Why you should back the Dodgers

Left fielder Teoscar Hernandez has been the most consistent playmaker on the offensive end for the Dodgers this series. Hernandez owns tremendous pop with the ability to push the ball into the gaps. Over four games, he leads the team in batting average (.333), RBI (6), and hits (5). On Oct. 8, he went 1-of-3 with a grand slam.

Ohtani remains one of the best hitters in recent history. Ohtani is a relentless slugger due to electric swing and gap-producing strength. During the regular season, he ranked second in the league in home runs (54) and RBI (130). In his last game, Ohtani went 1-of-3 with a base hit, one run driven in and two walks drawn. See which team to pick here.

Why you should back the Padres

The Padres hit Yamamoto hard in Game 1 of this season, scoring five runs and chasing him after just three innings and 60 pitches. Right fielder Fernando Tatis Jr. has been on fire in the 2024 MLB playoffs. This postseason, the 25-year-old ranks first on the team in batting average (.500), home runs (4), RBI (7), OBP (.577) and hits (11). In his last outing, Tatis went 1-of-4 with a double.

Third baseman Manny Machado can make an impact on both sides of the field. Machado will be a rangy defender with the arm strength to deliver strikes across the diamond. At the dish, he has home-run power and can be a solid run-producer. In the regular season, Machado hit .275 with 29 home runs and 105 RBI. In Game 3, he went 2-of-4 with two base hits and one run scored. See which team to pick here.

How to make Padres vs. Dodgers picks

SportsLine's model is leaning Over on the run total, projecting 8.4 combined runs. It also says one side of the money line has all the value. You can only get the MLB model's picks at SportsLine.

So who wins Padres vs. Dodgers, and which side has all the value? Visit SportsLine now to see which side you need to jump on, all from the model that's on a 32-17 roll on top-rated MLB run-line picks, and find out.