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Robert Hanashiro / USA TODAY Sports

The Minnesota Twins take on the Cincinnati Reds in an interleague matchup that gets the Tuesday MLB schedule underway. Both teams have struggled in 2021 and enter this showdown ranked fourth in their respective Central division. The Twins (31-41) have won the past five games, including a 7-5 victory over Cincinnati on Monday. The Reds (35-36) enter Tuesday's action on the heels of a five-game losing streak.

First pitch from the Target Field in Minneapolis is set for 1:10 p.m. ET. Minnesota is a -121 favorite (risk $121 to win $100) on the money line in the latest Reds vs. Twins odds from William Hill Sportsbook, while the over-under for total runs scored is nine. Before making any Twins vs. Reds picks, check out the latest MLB predictions and betting advice from the SportsLine Projection Model.

This model, which simulates every pitch of every game 10,000 times, had a banner 2019 season, the league's last full schedule, returning more than $1,400 on its top-rated money-line and run-line MLB picks. It's off to a sizzling start in 2021, going 100-74 on top-rated MLB money-line picks through 12 weeks, returning over $1,200. Anyone following it has seen huge returns.

Now, the model has dialed in on Twins vs. Reds. You can visit SportsLine now to see the picks. Here are the MLB lines and trends for Reds vs. Twins:

  • Reds vs. Twins money line: Minnesota -121, Cincinnati +110
  • Reds vs. Twins run line: Minnesota -1.5 (+160)
  • Reds vs Twins over-under: 9 runs
  • CIN: The Reds have returned +172 units on the money line when listed as an underdog this season.
  • MIN: The Twins have covered the spread in just 33 percent of their games as home favorites.
Featured Game | Minnesota Twins vs. Cincinnati Reds

Why you should back the Twins

The Twins haven't met expectations in 2021, but their bats have shown signs of life lately. Outfielder Max Kepler made a much-needed return to the lineup for MInnesota, and some of their other sluggers finally seem to have found their power stroke. Few MLB players have been hotter than Nelson Cruz, who homered against Cincinnati on Monday and brings an eight-game hit streak into Tuesday's contest.

Cruz has launched three home runs in his past five games, and he and fellow right-handed masher Miguel Sano present a real problem in the middle of Minnesota's lineup for Cincinnati's Tuesday starter, lefty Wade Miley. The bats aren't the only reason to be optimistic about Minnesota's chances -- rookie pitcher Bailey Ober has a sparkling 2.08 ERA across three June appearances, to go with a pristine 17-1 strikeout-to-walk ratio. If he can carry that success into Tuesday's matchup, Minnesota's revived bats should provide enough support to cover the spread.

Why you should back the Reds

Cincinnati's struggles -- both in their recent five-game losing streak and on the season as a whole -- have been largely due to inconsistency from their starting pitching. Between highly erratic play from their ace Luis Castillo and multiple injuries to other starters, it has been a struggle for Cincy to keep opposing teams off the scoreboard. And while Miley's peripherals do suggest that he has been out-performing his talent, he has been Cincinnati's most reliable starter in 2021. 

Offense hasn't been much of a problem for the Reds -- Nick Castellanos and Jesse Winker have been knocking the cover off of the ball for most of 2021, and many others have been finding their stroke recently. Both Eugenio Suarez and Aristides Aquino launched home runs in Monday's game, and rookie Jonathan India has hit his stride in June. Cincy's lineup will look to keep things going against Ober, who has given up three home runs already in 17 innings. 

How to make Reds vs. Twins picks

SportsLine's model is leaning over on the total, as the teams combine for 9.3 runs in the simulations, and it also says one side of the money line has all the value. You can only see the pick at SportsLine

So who wins Twins vs. Reds? And which side of the money line has all the value? Visit SportsLine now to see which side of the money line to jump on, all from the advanced model off to a hot start in 2021.