The third and final game of the series between the New York Yankees and Baltimore Orioles will take place on Wednesday with the Yankees looking to pull off a sweep at home. New York (48-38) won the first game 6-3 on a three-run homer by Harrison Bader in the eighth inning and then largely cruised to an 8-4 victory in Game 2. Now it will be Randy Vasquez taking the ball for the home team as they look to inch forward in the AL East race. Meanwhile, Dean Kremer takes the mound for the Orioles (49-35). 

The game is slated to begin at 7:05 p.m. ET at Yankee Stadium. Baltimore is the -120 favorite (risk $120 to win $100), while New York is a +100 underdog on the money line in the latest Yankees vs. Orioles odds from Caesars Sportsbook. The over/under for total runs scored is 9.5. Before making any Orioles vs. Yankees picks, be sure to check out the latest MLB predictions and betting advice from the SportsLine Projection Model.

The SportsLine Projection Model simulates every MLB game 10,000 times. It went 331-285 on top-rated MLB money-line picks (+357) over the past two seasons. It has excelled on top-rated run-line picks this season, going 11-2 (+604). Anybody following has seen big returns.   

Now, the model has set its sights on Yankees vs. Orioles and just locked in its picks and MLB predictions. You can head to SportsLine now to see the model's picks. Here are several MLB betting lines and trends for Orioles vs. Yankees:

  • Yankees vs. Orioles money line: Yankees +100, Orioles -120
  • Yankees vs. Orioles run line: Yankees +1.5 (-160)
  • Yankees vs. Orioles over/under: 9.5 runs
  • NYY: New York has won five of its last seven overall
  • BAL: Baltimore has lost six of seven overall
  • Yankees vs. Orioles picks: See picks at SportsLine

Why you should back the Yankees

The Yankees will continue to lean on their dominant bullpen with Vasquez (1-1, 1.74 ERA) making just his third career start. New York's pen has the lowest ERA in Major League Baseball in 2023 and they've given up just one run over 8 2/3 innings so far in this series. 

Given the number of innings that they've been used over the first two games, will Aaron Boone still have the depth to survive if Vazquez can't get into the sixth or seventh inning? Meanwhile, Bader has five RBI this series and Gleyber Torres is coming off a big game on Tuesday, going 2-for-4 with a home run, two RBI and three runs scored. See which team to back here.

Why you should back the Orioles

Baltimore will be hoping to get more out of their production at the plate on Wednesday. The Orioles have had 20 hits over the first two games with 15 of 18 starters recording hits during that span. However, the Orioles have only managed seven runs thanks to 15 runners stranded. 

They could be in line for better fortune against Vazquez on Wednesday and they'll be hoping for a bounce-back start from Kremer (8-4, 5.04 ERA). Kremer gave up seven earned runs in his last start, but had gone at least five innings while giving up three earned runs or less in nine of his previous 10 starts. See which team to back here.

How to make Orioles vs. Yankees picks

SportsLine's model is leaning Under on the total, projecting 9.1 combined runs. It also says one side of the money line has all of the value. You can only get the model's MLB picks at SportsLine.

So who wins Yankees vs. Orioles, and which side has all the value? Visit SportsLine now to see which side you need to jump on, all from the model that has gone 11-2 on its top-rated MLB run-line picks, and find out.