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Two title matches are on tap for Saturday night when UFC 266 goes down in Las Vegas. Alexander Volkanovski will put his featherweight championship on the line against former title challenger Brian Ortega in the main event with Valentina Shevchenko defending the women's flyweight championship against Lauren Murphy.

The Aussie enters on an incredible 19-fight win streak that includes nine inside the UFC Octagon. He's beaten some of the biggest names in the sport -- Max Holloway twice as well as Jose Aldo -- en route to capturing the 145-pound title. Now, he takes on the latest challenger in Ortega after seeing some bad blood spill over from their duties as coaches on "The Ultimate Fighter". Ortega enters red hot after bouncing back from a loss to Holloway in a title challenge in 2018 thanks to a dominant win over the Korean Zombie.

Plus, the long awaited return of Nick Diaz is set for a featured contest on the main card when he takes on former welterweight champion Robbie Lawler. The two previously met all the way back in 2004 with Diaz scoring a brutal knockout. This will be Diaz's first fight since January 2015 after a lengthy battle with the Nevada State Athletic Commission over failed test for marijuana.

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Below is all the information you need to catch UFC 266 on Saturday night. 

How to watch UFC 266 prelims

Date: Sept. 25 | Location: T-Mobile Arena -- Las Vegas, Nevada
Time: 8 p.m. ET
TV: ESPN News | Stream: fuboTV (try for free)

How to watch UFC 266 main card

Date: Sept. 25 | Location: T-Mobile Arena -- Las Vegas, Nevada
Time: 10 p.m. ET
Stream: ESPN+ | Price: $69.99

Now, here's a look at the UFC 266 main fight card and betting odds via Cesars Sportsbook.

UFC 266 main card, odds

FavoriteUnderdogWeightclass

Alexander Volkanovski (c) -180

Brian Ortega +155

Featherweight championship

Valentina Shevchenko (c) -1500

Lauren Murphy +850

Women's flyweight championship

Robbie Lawler -160

Nick Diaz +135

Middleweight

Curtis Blaydes -340

Jairzinho Rozenstruik +270

Heavyweight

Jessica Andrade -240

Cynthia Calvillo +200

Women's flyweight


Who will win Volkanovski vs. Ortega? And how exactly does each UFC 266 fight end? Visit SportsLine now to get detailed picks from Kyle Marley, who's up over $14,000 on MMA picks in the past 31 months, and find out.