Watch Now: UFC Fight Night Preview: Dustin Poirier vs Dan Hooker (1:26)

Dustin Poirier, the third-ranked UFC lightweight contender, has just two losses since 2014. Many of his wins have come in memorable fashion, with his last five victories being named Fight of the Night. He could be one of the most popular UFC DFS picks on Saturday on sites like FanDuel and DraftKings when he takes on No. 5 Dan Hooker in the main event of UFC Fight Night: Poirier vs. Hooker at the UFC Apex Facility in Las Vegas.

Poirier is also the highest-priced option in the MMA DFS fighter pool on both sites, so does he have enough value to build your UFC DFS lineups around? And which other fighters on Saturday's Fight Night card should be part of your UFC Fight Night DFS strategy? Before you make any UFC DFS picks for Fight Night: Poirier vs. Hooker, be sure to check out the optimal UFC DFS strategy and advice from SportsLine's Mike McClure.

McClure is a predictive data engineer and DFS pro with almost $2 million in career winnings. He's crushed his DFS selections recently, producing tournament rosters that have cashed huge in multiple sports over the past few years.

At UFC Fight Night: Blaydes vs. Volkov, McClure was all over Curtis Blaydes as his top pick. The results: Blaydes landed 69 significant strikes and had a whopping 14 takedowns in a decision victory, and anybody who followed McClure's advice was poised for a profitable day.

Now, McClure has set his sights on UFC Fight Night: Poirier vs. Hooker and locked in his top MMA daily Fantasy picks. You can only see them here.

Top UFC Fight Night: Poirier vs. Hooker DFS predictions

For UFC Fight Night: Poirier vs. Hooker, McClure is high on Dustin Poirier at $22 on FanDuel and $8,700 on DraftKings. After knocking out Justin Gaethje and Eddie Alvarez in 2018, Poirier earned the right to fight for the interim UFC Lightweight Championship against Max Holloway. He won the belt in a unanimous decision before being submitted by Khabib Nurmagomedov for the undisputed title last September.

Poirier is  25-6-1 in his career and could have a significant striking advantage against Hooker, which should translate to plenty of UFC DFS production. Poirier lands 5.59 significant strikes per minute to Hooker's 4.35, while Hooker eats 5.13 significant strikes per minute to Poirier's 3.69. Poirier is also the superior wrestler, so Hooker (20-8) won't have many avenues to escape a striking battle.

Part of McClure's optimal UFC DFS strategy also includes rostering Brendan Allen (14-3) at $9,200 on DraftKings and $18 on FanDuel. He's one of the biggest favorites on the card as he takes on Kyle Daukaus (9-0) in a battle of fighters hoping to make noise in the middleweight class. Allen was a star in the Legacy Fighting Alliance and Contender Series before getting off to a 2-0 start at the UFC level.

He beat Kevin Holland via submission at a Fight Night last October and then knocked out Tom Breese in the first round at UFC Fight Night: Benavidez vs. Figueiredo earlier this year. McClure has considered that Allen is an accomplished wrestler who also has plenty of power. With five career wins via TKO and eight via submissions, Allen has shown he knows how to end a fight before it gets to the scorecards, making him one of the optimal UFC DFS picks for Saturday. 

How to make UFC DFS picks

McClure is also targeting a value fighter who is a must-roster because his fight is a huge mismatch. This pick could be the difference between cashing huge in MMA DFS or going home with nothing. You can see all of McClure's MMA DFS picks and advice here.

So what are the optimal DraftKings and FanDuel picks for UFC Fight Night: Poirier vs. Hooker? And which value fighter needs to be in your lineup? Visit SportsLine now to see DFS millionaire Mike McClure's complete optimal picks for Saturday's UFC Fight Night, and cash in big on MMA DFS.