IndyCar: 103rd Running of the Indianapolis 500-Practice
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The greatest spectacle in motor racing, the 2021 Indianapolis 500 is set for Sunday at the fabled Indianapolis Motor Speedway. The 2.5-mile speedway has hosted 104 previous runnings of the Indianapolis 500, and this year's event welcomes back fans to the Brickyard after the 2020 running was held without spectators and returns to its traditional Memorial Day weekend schedule after being run in August last year. The green flag drops at 11 a.m. ET, with 2008 champion Scott Dixon on the pole.

Dixon is the favorite at 4-1 in the latest 2021 Indianapolis 500 odds at William Hill Sportsbook, but is followed closely by Colton Herta at 7-1. Two-time winner and defending Indy 500 champ Takuma Sato is 17-1 on the Indy 500 odds board. Before making any 2021 Indianapolis 500 picks, be sure to see the latest 2021 Indy 500 predictions and projected leaderboard from the model at SportsLine.

Developed by daily Fantasy pro and SportsLine predictive data engineer Mike McClure, this proprietary racing prediction model simulates every race 10,000 times, taking into account factors such as track history and recent results.

It has made some huge calls in NASCAR, and in IndyCar, it called five of the top-10 finishers in the Indianapolis 500 in both 2018 and 2019, and six out of the top 10 in 2020. The model knows what it takes to contend in Indianapolis, and anybody who has followed it has seen some big returns.

Now, the model simulated the Indianapolis 500 2021 on Sunday, May 30, 10,000 times. Head here to see the complete projected leaderboard.

Top 2021 Indianapolis 500 predictions

For the 2021 Indianapolis 500, the model is high on Ed Carpenter, even though he's a 25-1 long shot in the latest 2021 Indy 500 odds. Carpenter is a target for anyone looking for a huge payday. The 40-year-old American has come so close to kissing Indy's yard of bricks over the years, but has yet to find Victory Lane at IMS.

Carpenter has earned the pole position three times in 17 Indianapolis 500 starts, taking the green flag first in 2013, 2014 and 2018. Carpenter's 2018 run at Indy was his closest yet to putting his face on the Borg-Warner Trophy, as he finished second that year – leading 65 laps but falling to Will Power at the end. The stepson of Indy Racing League founder Tony George, Carpenter has been driving for his own team since 2016 and has piloted a Dallara Chevrolet since 2012. Despite the disadvantages of driving for a smaller team, Carpenter has shown he can be fast at IMS and is a great choice for 2021 Indianapolis 500 bets. 

And a massive shocker: Patricio O'Ward, one of the top favorites at 15-2, stumbles big-time and barely cracks the top five. There are far better values in this loaded 2021 Indianapolis 500 starting lineup. At age 22, he's already in his fourth IndyCar season.

He's a bright young star who won at Texas already this season. But he's still looking for a breakout moment at Indianapolis. He hasn't finished better than fifth at this track and settled for a disappointing 15th place last week at this track, making him one of the Indy 500 contenders to avoid. 

How to make 2021 Indianapolis 500 picks

The model is also targeting three other drivers with 2021 Indianapolis 500 odds of 14-1 or longer to make a serious run at the checkered flag, including a massive long shot. Anyone who backs these drivers could hit it big. You can only see them here.

So who wins Sunday's Indianapolis 500 2021? And which long shots stun IndyCar? Check out the latest odds below and then visit SportsLine now to see the full projected 2021 Indy 500 leaderboard, all from the model that has crushed its NASCAR picks and called at least five of the top 10 drivers at the Indianapolis 500 the past three years, and find out.

2021 Indianapolis 500 odds (via William Hill)

Scott Dixon 4-1
Colton Herta 7-1
Pato O'Ward 15-2
Alex Palou 10-1
Josef Newgarden 12-1
Alexander Rossi 12-1
Tony Kanaan 14-1
Rinus VeeKay 17-1
Takuma Sato 17-1
Ryan Hunter-Reay 18-1
Graham Rahal 20-1
Marcus Ericsson 20-1
Simon Pagenaud 22-1
Will Power 22-1
Ed Carpenter 25-1
Scott McLaughlin 25-1
Juan Pablo Montoya 28-1
Helio Castroneves 30-1
Marco Andretti 40-1
Conor Daly 40-1
Felix Rosenqvist 50-1
James Hinchcliffe 50-1
Ed Jones 60-1
Santino Ferrucci 60-1
Jack Harvey 75-1
Sebastien Bourdais 100-1
Sage Karam 100-1
Stefan Wilson 125-1
J.R. Hildebrand 150-1
Pietro Fittipaldi 200-1
Dalton Kellett 500-1
Max Chilton 500-1
Simon de Silvestro 500-1