After serving as a replacement for Watkins Glen last season, the Daytona Road Course will host its own NASCAR race on Sunday. The green flag drops on the 2021 O'Reilly Auto Parts 253 at 3 p.m. ET and there will be plenty on the line in NASCAR DFS tournaments, cash games and 50-50s on sites like FanDuel and DraftKings. Michael McDowell is coming off a stunning win in the Daytona 500, but has just one top-10 finish in 23 career road races in the NASCAR Cup Series. Can you trust him with your NASCAR DFS picks?

Chase Elliott has won the last four NASCAR Cup Series road races and enters the week as the priciest driver on DraftKings and the second-most expensive option on FanDuel. Is Elliott worth the price for your 2021 O'Reilly Auto Parts 253 DFS lineups, and which value plays should you target in the NASCAR DFS driver pool? Before finalizing your NASCAR DFS picks for the 2021 O'Reilly Auto Parts 253 on sites like DraftKings and FanDuel, be sure to check out the optimal 2021 O'Reilly Auto Parts 253 NASCAR DFS strategy and advice from SportsLine's Mike McClure.

McClure has won almost $2 million in his career as a daily Fantasy pro, and his NASCAR DFS driver pool, projections and advice can help you score a big win on Sunday. McClure dominated NASCAR DFS at the 2020 Daytona 500, turning a 4x ROI after rostering four of the top seven drivers. 

He then crushed the 2020 Real Heroes 400, with his top three picks -- Denny Hamlin, Erik Jones and Martin Truex Jr. -- all finishing in the top eight. He also had Truex Jr. at No. 1 in his DraftKings value rankings for his win at Martinsville and then had Kevin Harvick at No. 1 for his win at Indianapolis. Anybody who has followed his picks has seen huge returns. 

Now, he's turned his attention to Sunday's 2021 O'Reilly Auto Parts 253. He's only sharing his picks and NASCAR DFS driver pool here.

Top 2021 O'Reilly Auto Parts 253 NASCAR DFS picks

For the Daytona road race, McClure is high on Tyler Reddick ($7,000 on FanDuel and $7,500 on DraftKings). The 2018 and 2019 NASCAR Xfinity Series champion had a solid rookie season, finishing 19th in the standings after recording nine top-10s and three top-fives in 2020.

Reddick proved to be a formidable road racer despite the general lack of experience, finishing 12th on the Charlotte Roval, 18th in the first ever race on the Daytona Road Course and fourth in the 2021 Busch Clash on the same track last week. Reddick has four top-five finishes in eight career starts on road courses while in the Xfinity Series and the 25-year-old would love to establish the No. 8 Chevrolet as one to watch in road races going forward.

Part of his optimal NASCAR DFS strategy includes rostering Martin Truex Jr. at $14,000 on FanDuel and $10,700 on DraftKings. Truex is one of the top road racers in the sport, with four wins on road courses and 17 top-10 finishes in 32 career starts.

Truex led 10 laps and finished third in the first-ever race on the Daytona Road Course and led multiple laps during the 2021 Busch Clash on the same track before a crash took him out. He's a strong bet to work his way into contention on Sunday.

How to set 2021 O'Reilly Auto Parts 253 NASCAR DFS lineups

McClure is also targeting an undervalued driver set to return plenty of value. He's in prime position to make a run at the checkered flag and comes at a price that won't break the bank. This pick could be the difference between cashing huge in your NASCAR DFS tournaments and cash games or going home with nothing. You can see every pick here.

So what are the top NASCAR DFS picks for Sunday's 2021 O'Reilly Auto Parts 253? And which value driver is a must-roster? Visit SportsLine now to see DFS millionaire Mike McClure's complete driver pool for DraftKings and FanDuel, and cash in big on NASCAR at Daytona.