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The Indiana Pacers will take on the Philadelphia 76ers on Saturday evening at Gainbridge Fieldhouse. The Pacers are 5-8 overall and 3-2 at home, while Philadelphia is 8-5 overall and 4-1 on the road. Both sides are 7-6 against the spread this season, though the Sixers do enter this matchup on an 0-3 ATS run. 

Tipoff is set for 7 p.m. ET. Indiana is favored by 2.5 points in the latest Pacers vs. 76ers odds from Caesars Sportsbook, and the over-under is set at 217.5. Before entering any 76ers vs. Pacers picks, you'll want to see the NBA predictions from the model at SportsLine.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned over $9,000 in profit on its top-rated NBA picks over the past three-plus seasons. The model enters Week 4 of the 2021-22 NBA season up over $500 on all top-rated NBA picks this season. It's also on a stunning 110-73 roll on top-rated NBA picks against the spread that dates back to last season. Anyone following it has seen huge returns.

Now, the model has set its sights on Pacers vs. Sixers. You can head to SportsLine to see its picks. Here are several NBA betting lines for Sixers vs. Pacers:

  • 76ers vs. Pacers spread: Pacers -2.5
  • 76ers vs. Pacers over-under: 218 points
Featured Game | Indiana Pacers vs. Philadelphia 76ers

What you need to know about the Pacers

Indiana strolled past the Utah Jazz with points to spare on Thursday, taking the contest 111-100. Indiana's success was spearheaded by the efforts of point guard Malcolm Brogdon, who had 30 points in addition to nine boards, and point guard T.J. McConnell, who had 21 points and five assists along with eight rebounds.

Brogdon leads the team with 23.6 points per game. Domantas Sabonis is averaging 18.3 points and 11.2 rebounds. Third-leading scorer Caris LeVert (17.2 ppg) is questionable with a back injury. 

What you need to know about the 76ers

Meanwhile, the Sixers were within striking distance but couldn't close the gap on Thursday as they fell 115-109 to the Toronto Raptors. Point guard Tyrese Maxey put forth a good effort for the losing side as he had 33 points and five assists.

The Sixers have been hit hard by injuries and other personnel issues. In addition to Ben Simmons' indefinite absence from the team, the 76ers will be without Joel Embiid, Matisse Thybulle and Isaiah Joe due to COVID-19 protocols on Saturday. Tobias Harris, however, did return to the lineup last game and put together a solid 19-point performance with seven rebounds and seven assists. 

How to make Pacers vs. Sixers picks

The model is leaning under on the total, and it also says one side of the spread has all the value. You can only see the pick at SportsLine.

So who wins Pacers vs. 76ers? And which side of the spread has all the value? Visit SportsLine now to find out, all from the model that has crushed its NBA picks