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The Indiana Pacers will take on the Portland Trail Blazers at 10 p.m. ET on Friday at the Moda Center at the Rose Quarter. Portland is 3-5 overall and 3-1 at home, while the Pacers are 3-6 overall and 0-4 on the road. The Blazers have dominated this series in recent years, winning seven of their last 10 meetings against Indiana. 

Portland is favored by 4.5-points in the latest Blazers vs. Pacers odds from Caesars Sportsbook, and the over-under is set at 223.5. Before entering any Pacers vs. Blazers picks, you'll want to see the NBA predictions from the proven computer model at SportsLine.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned almost $9,000 in profit on its top-rated NBA picks over the past three-plus seasons. The model finished up almost $600 on its top-rated picks last season and enters Week 3 of the 2021-22 NBA season on a stunning 106-71 roll on top-rated NBA picks against the spread. Anyone following it has seen huge returns.

Now, the model has set its sights on Blazers vs. Pacers. You can head to SportsLine to see its picks. Here are several NBA betting lines for Blazers vs. Pacers:

  • Trail Blazers vs. Pacers spread: Portland -4.5
  • Trail Blazers vs. Pacers over-under: 223.5 points

What you need to know about the Trail Blazers

It was close but no cigar for the Blazers as they fell 107-104 to the Cleveland Cavaliers on Wednesday. Shooting guard Norman Powell put forth a good effort for the losing side as he had 23 points. Damian Lillard also had a strong showing in the loss, recording 26 points, eight assists and three rebounds. For the season, Lillard is averaging 19.5 points, 8.5 assists and 3.9 rebounds per game. 

The Blazers are averaging 111.0 points per game this season, the seventh-best mark in the NBA. Portland has also been hard to beat on its home court, winning eight of its last 11 games at home. However, the Blazers are 1-4 against the spread in their last five games against an opponent from the Eastern Conference. 

What you need to know about the Pacers

Meanwhile, Indiana didn't have too much trouble with the New York Knicks at home on Wednesday as the Pacers won 111-98. Indiana's power forward Myles Turner was one of the most active players for the team, shooting 7-for-10 from downtown and finishing with a double-double with 25 points and 13 rebounds along with three blocks.

The Pacers have lost 11 of their last 12 games on the road against the Blazers. However, Indiana is 5-1 against the spread in its last six games played in November. 

How to make Pacers vs. Blazers picks

The model has simulated Blazers vs. Pacers 10,000 times and the results are in. We can tell you that the model is leaning over, and it's also generated a point-spread pick that is hitting in over 70 percent of simulations. You can only see the pick at SportsLine.

So who wins Pacers vs. Blazers? And which side of the spread hits in over 70 percent of simulations? Visit SportsLine now to find out which side of the Blazers vs. Pacers spread you need to jump on Friday, all from the model that has crushed its NBA picks, and find out.