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The Portland Trail Blazers will take on the San Antonio Spurs at 8:30 p.m. ET on Friday at AT&T Center. San Antonio is 26-27 and has lost six of its last eight games while Portland is 31-23 and has lost four of its last five. The Blazers are currently the sixth seed in the Western Conference while the Spurs sit at the 10th seed, which is the last play-in spot. This is the second of three matchups between these Western Conference foes with the Spurs winning 125-104 in a January meeting. 

Portland is favored by two points in the latest Spurs vs. Blazers odds from William Hill Sportsbook, and the over-under is set at 232.5. Before entering any Blazers vs. Spurs picks, you'll want to see the NBA predictions from the model at SportsLine.

The SportsLine Projection Model simulates every NBA game 10,000 times, and it has returned over $9,100 in profit on its top-rated NBA picks over the past two-plus seasons. The model is up over $1,100 on its top-rated picks this season, and dating back to last year, it entered Week 17 of the 2020-21 NBA schedule on a stunning 95-59 roll on top-rated NBA picks against the spread. Anybody who has followed it has seen huge returns.

Now, the model has set its sights on Spurs vs. Trail Blazers. You can head to SportsLine to see its picks. Here are several NBA betting lines for Trail Blazers vs. Spurs:

  • Spurs vs. Trail Blazers spread: Blazers -2
  • Spurs vs. Trail Blazers over-under: 232.5 points
  • Spurs vs. Trail Blazers money line: Blazers -135, Spurs +115

What you need to know about the Spurs

The Spurs were within striking distance but couldn't close the gap on Wednesday as they fell 117-112 to the Toronto Raptors. San Antonio's loss shouldn't obscure the performances of DeMar DeRozan, who dropped a double-double with 19 points and 11 assists, and Derrick White, who finished with a team-high of 25 points. 

DeRozan is having his best all-around year which comes in his 12th NBA season. He leads the Spurs with 21.1 points per game while also dishing out a career-high of 7.2 assists per game. As San Antonio's primary playmaker, DeRozan has also done a great job of protecting the ball as the Spurs commit the fewest turnovers in the league. The Spurs have a 20-16 record when they commit 12 or fewer turnovers but are just 6-11 when committing 13 or more turnovers in a game.

What you need to know about the Trail Blazers

Meanwhile, Rip City was just a bucket short of a victory on Tuesday and fell 116-115 to the Boston Celtics. The Blazers had three players with at least 20 points with Damian Lillard (28 points), Carmelo Anthony (25 points) and Norman Powell (20 points). CJ McCollum also chipped in with 16 points but did it on poor shooting, going 6-for-19 from the field.

Lillard is having an MVP-caliber season with 28.7 points per game and 7.7 assists per game. The Blazers are a perfect 7-0 when he scores at least 39 points and are 10-1 when he scores at least 36 points. He is the catalyst for Portland's attack from beyond the arc as the Blazers rank second in made 3-pointers, second in attempted 3-pointers and sixth in 3-point percentage. 

How to make Trail Blazers vs. Spurs picks

The model has simulated Spurs vs. Trail Blazers 10,000 times and the results are in. It is leaning under on the total, and it's also generated a point-spread pick that hits in well over 50 percent of simulations. You can only see the pick at SportsLine.

So who wins Trail Blazers vs. Spurs? And which side of the spread hits in well over 50 percent of simulations? Visit SportsLine now to find out which side of the spread you need to jump on, all from the model that is on a 95-59 roll on NBA picks.