The Los Angeles Clippers play host to the Cleveland Cavaliers in a nationally televised, cross-conference matchup on Tuesday evening. Paul George (hamstring) will miss the game for the Clippers, while the Cavaliers enter Tuesday's matchup on the second night of a back-to-back after losing to the Lakers on Monday. 

Tip-off is at 10:30 p.m. ET at the Staples Center. Sportsbooks list the Clippers as 15-point home favorites, holding steady from the opener, while the over-under, or total number of points Vegas thinks will be scored, is 224 in the latest Cavaliers vs. Clippers odds. Before you make any Clippers vs. Cavaliers picks and NBA predictions, you'll want to see what SportsLine's advanced computer model has to say.

The SportsLine Projection Model simulates every NBA game 10,000 times, and last season it returned a whopping $4,280 on its top-rated NBA spread and money line picks. It's already returned over $2,000 in profit on all its top-rated NBA picks during the 2019-20 season and entered Week 12 on a blistering 28-16 run on all top-rated NBA spread picks. Anybody who has followed it has seen huge returns.

Now, the model has set its sights on Cavaliers vs. Clippers. You can head to SportsLine to see its picks. Now, here are several NBA betting lines and trends for Clippers vs. Cavaliers:

  • Cavaliers vs. Clippers spread: Clippers -15
  • Cavaliers vs. Clippers over-under: 224 points
  • Cavaliers vs. Clippers money line: Clippers -1232, Cavaliers +890
  • CLE: The Cavaliers have covered the spread in three of their last four games.
  • LAC: The Clippers have failed to cover the spread in four straight.

Why the Cavaliers can cover

The model understands that Cleveland is in a difficult schedule spot but, in recent days, the Cavaliers are showing signs of life. They picked up back-to-back road wins over the Pistons and Nuggets last week and, for a half against the Lakers, Cleveland was competitive. 

John Beilein's team is the best in the NBA on the offensive glass, creating extra opportunities for easy baskets near the rim. In addition, Cleveland is the best in the league at avoiding defensive fouls, which counteracts a major strength of the Clippers' offense in generating free throw attempts. Even so, Cleveland isn't a lock to cover the Cavaliers vs. Clippers spread on Tuesday night.

Why the Clippers can cover

The model also knows that George's absence is not a small factor, but the Clippers are playing at home and have the rest advantage. From a schematic standpoint, Los Angeles is elite at creating extra possessions on the offensive glass and, overall, the Clippers rank easily as a top 10 offense. In fact, the Clippers enter Tuesday's matchup averaging 115.3 points per game, good for fourth-best in the league. 

Defensively, the Clippers have a fantastic overall profile that ranks them as an elite group. That is headlined by some of the best shot resistance metrics in the NBA, and this is a supremely favorable matchup against a Cleveland team that sometimes struggles to score in an efficient and effective manner. Plus, the Clippers are 4-2 against the spread in their last six home games against Cleveland. 

How to make Cavaliers vs. Clippers picks

SportsLine's model is leaning over on the total, and it also says one side of the spread hits in well over 50 percent of simulations.

So who wins Clippers vs. Cavaliers? And which side of the spread hits in well over 50 percent of simulations? Visit SportsLine now to find out which side of the Cavaliers vs. Clippers spread you need to jump on, all from the model that has crushed its NBA picks, and find out.