The New York Knicks welcome the Philadelphia 76ers to Madison Square Garden for a nationally televised game on Tuesday evening. The Knicks opened the season with two victories before losing to the Orlando Magic on Sunday. Most of the attention paid to Philadelphia this season revolves around the continued absence of Ben Simmons. However, the 76ers are 2-1 in the standings and led by a superstar in Joel Embiid.

Caesars Sportsbook lists New York as a two-point home favorite, and tip-off is scheduled for 7:30 p.m. ET. The total number of points Vegas thinks will be scored, or the over-under, is 217 in the latest 76ers vs. Knicks odds. Before entering any Knicks vs. Sixers picks, you'll want to see the NBA predictions from the model at SportsLine.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned almost $9,000 in profit on its top-rated NBA picks over the past three-plus seasons. The model finished up almost $600 on its top-rated picks last season and enters Week 2 of the 2021-22 NBA season on a stunning 103-68 roll on top-rated NBA picks against the spread. Anyone following it has seen huge returns.

Now, the model has set its sights on Knicks vs. Sixers. You can head to SportsLine to see its picks. Here are several NBA betting lines for Knicks vs. 76ers:

  • 76ers vs. Knicks spread: Knicks -2
  • 76ers vs. Knicks over-under: 217 points
  • 76ers vs. Knicks money line: Knicks -140, 76ers +120
  • Philadelphia: The 76ers are 21-20-2 against the spread in the last 43 road games
  • New York: The Knicks are 25-16 against the spread in the last 41 home games
Featured Game | New York Knicks vs. Philadelphia 76ers

Why the 76ers can cover

Philadelphia is playing at a very high level in the early going. The 76ers are scoring 1.16 points per possession through three games, out-scoring opponents by a whopping 9.2 points per 100 possessions. Those are elite figures, and Philadelphia's defense has been strong anytime Embiid has been active and healthy for several years. 

Offensively, Philadelphia is taking care of the ball at a high level, committing a turnover on only 11.9 percent of possessions to this point, and the 76ers sport a 59.5 percent true shooting mark that is elite. Part of that efficiency can be traced to a scorching-hot start from Seth Curry, who is averaging 20.5 points per game and making 76.5 percent of his three-point attempts. With Philadelphia facing a New York team with a below-average offense dating back to last season, the 76ers should be in a favorable position at home.

Why the Knicks can cover

New York's defense is elite, dating back to last season. The Knicks led the NBA in both field-goal percentage allowed (44 percent) and 3-point percentage allowed (33.7 percent) a season ago, ranking in the top five in overall defensive rating. New York is well-coached under Tom Thibodeau, ranking near the top of the NBA in assists allowed (23.6 per game), fast-break points allowed (10.5 per game) and points in the paint allowed (43.8 per game) a season ago. 

This year, the Knicks are limiting opponents to 104.9 points per 100 possessions, an elite figure, and New York is also playing better basketball offensively. The Knicks are assisting on 61.4 percent of their field goals through three games, with only a 12.9 percent turnover rate to boot. Julius Randle has emerged as a legitimate star after averaging 24.1 points, 10.2 rebounds and 6.0 assists per game last season, and the Knicks have increased firepower after myriad offseason transactions.

How to make Sixers vs. Knicks picks

The model is leaning over on the total, projecting the teams to combine for 220 points. It also has generated a spread pick that hits in well over 50 percent of simulations. You can only see the pick at SportsLine

So who wins Knicks vs. 76ers? And which side of the spread hits in well over 50 percent of simulations? Visit SportsLine now to find out which side of the spread to back, all from the model that has crushed its NBA picks, and find out.