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The Los Angeles Lakers welcome the Portland Trail Blazers to the STAPLES Center on Friday evening. The Lakers are 22-11 overall this season, though the team has a 9-7 home record and enters on a four-game losing streak. The Blazers are 18-13 overall after losing the last three games. Anthony Davis (calf) is out for Los Angeles, with CJ McCollum (foot) and Jusuf Nurkic (wrist) ruled out for Portland.

Tip-off is at 10 p.m. ET in Los Angeles. William Hill Sportsbook lists the Lakers as five-point home favorites, while the over-under, or total number of points Vegas thinks will be scored, is 222 in the latest Blazers vs. Lakers odds. Before you make any Lakers vs. Blazers picks, be sure to see the NBA predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every NBA game 10,000 times, and it returned over $5,000 in profit on its top-rated NBA picks last season. The model also is up almost $8,700 on top-rated NBA picks over the past two-plus seasons. Dating back to last season, it enters Week 10 of the 2020-21 NBA schedule on a stunning 85-49 roll on top-rated NBA picks against the spread. Anybody who has followed it has seen huge returns.

Now, the model has set its sights on Blazers vs. Lakers. You can head to SportsLine to see its picks. Now, here are several NBA odds and betting trends for Lakers vs. Blazers:

  • Blazers vs. Lakers spread: Lakers -5
  • Blazers vs. Lakers over-under: 222 points
  • Blazers vs. Lakers money line: Lakers -200, Blazers +175
  • POR: The Blazers are 7-3 against the spread in the last 10 games
  • LAL: The Lakers are 2-8 against the spread in the last 10 games

Why the Trail Blazers can cover

Injuries have affected the Blazers throughout the season, but Portland's overall play has stabilized thanks to the play of Damian Lillard. The All-NBA guard is averaging 29.6 points and 8.0 assists per game, putting pressure on the opposition for every minute that he is on the floor. Lillard is the central reason that Portland currently ranks seventh-best in the NBA in offensive rating (115.2 points per 100 possessions), and he creates avenues for others. 

The Blazers are also No. 2 in the league in ball security, turning the ball over on only 11.5 percent of possessions, and Portland is an above-average offensive rebounding team, creating extra shots. Defensively, the Blazers excel at limiting points off turnovers, giving up only 14.7 points per game, and the Lakers are also prone to giveaways, committing a turnover on 15.2 percent of possessions this season.

Why the Lakers can cover

The Lakers are off to a relatively slow start offensively this season, in part due to personnel limitations. Still, Los Angeles has LeBron James to act as an offensive engine, and he is averaging 25.6 points, 8.1 rebounds and 8.0 assists per game in 2020-21. From there, the Lakers should be able to create efficient offense against Portland, as the Blazers are the second-worst team in the NBA in defensive rating, giving up 1.16 points per possession. 

Portland ranks as a bottom-tier team in turnover creation, forcing a giveaway on only 12.9 percent of possessions. In addition, the Blazers are a bottom-eight team in free throw creation allowed and shooting efficiency allowed, with considerable holes in their defensive resistance.

How to make Lakers vs. Blazers picks

SportsLine's model is leaning over on the total, projecting both teams combine for 226 points. The model also says one side of the spread hits in over 60 percent of simulations. You can get that pick at SportsLine.

So who wins Blazers vs. Lakers? And which side of the spread hits over 60 percent of the time? Visit SportsLine now to find out which side of the spread you need to jump on, all from the model that has crushed its NBA picks.