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The Boston Celtics and Miami Heat will go head-to-head in Game 4 of the 2020 NBA Eastern Conference Finals on Wednesday night at 8:30 p.m. ET. There's big money on the line in NBA daily Fantasy tournaments, cash games and 50-50s on sites like FanDuel and DraftKings for Celtics vs. Heat. The Heat have a 2-1 advantage but the Celtics are coming off a Game 3 victory where they had four players score at least 20 points. Jaylen Brown led the team in scoring with 26 points and he's now scored at least 20 in five of his last six games to become a popular option for NBA DFS lineups.

However, with at least 10 players reaching double-figures in scoring in each of the first three games of this series, the Celtics vs. Heat NBA DFS player pool is surprisingly deep for a single-game slate. That means getting value into your squad is critical in affording some of the bigger-name talent with higher upside like Brown or Bam Adebayo. So before locking in any NBA DFS lineups for Game 4 of Celtics vs. Heat, don't miss the NBA DFS advice, core lineup picks and player rankings from SportsLine's Mike McClure, a daily Fantasy pro who has won almost $2 million in his career. 

McClure is also a predictive data engineer at SportsLine who uses a powerful prediction model that simulates every minute of every game 10,000 times, taking factors like matchups, statistical trends and injuries into account. This allows him to find the best NBA DFS values and create optimal lineups that he shares only over at SportsLine. They're a must-see for any NBA DFS player.

McClure rolled through the 2018-19 NBA season, producing multiple lineups that led to huge returns for followers, including as much as 40x on FanDuel and 84x on DraftKings. He saw multiple huge cashes again early in the 2019-20 NBA season and got 2020 off to a blistering start with his optimal lineup returning at least 7x on DraftKings on three of the first five days of the new year. He's returned 4x or more multiple times since that point. Anybody following him has seen huge returns. 

The last time these teams met on Saturday, McClure identified Celtics forward Jayson Tatum as one of his top picks. The result: Tatum filled the stat sheet with 25 points, 14 rebounds and eight assists -- putting up over 55 points on DraftKings.

Now he's turned his attention to Wednesday's single-game Heat vs. Celtics DFS slate. Head to SportsLine to see his optimal NBA DFS picks

McClure's top NBA DFS picks for Sept. 23

For Wednesday, McClure is high on Celtics forward Jayson Tatum. The 22-year-old has emerged as a star this season, making his first NBA All-Star appearance and averaging 23.4 points and 7.0 rebounds per game during the regular season.

However, he's really captured the attention of the basketball world this postseason, averaging 25.3 points, 10.3 rebounds and 4.6 assists per game. Tatum has seven 20 and 10 double-doubles already this postseason and he's coming off a 25-14-8 stat line in Monday's Game 3 win. He's had tremendous success throughout the playoffs, so you can confidently roster him in your Celtics vs. Heat NBA DFS lineups on Wednesday.

Part of McClure's optimal NBA DFS strategy for Wednesday also includes rostering Celtics guard Kemba Walker. The former Hornets star knew he'd be in for a smaller scoring role on a more competitive team when he signed with Boston during free agency, but he's still capable of going off on any given night.

Walker has averaged 21.0 points per game so far this series and has seven 20-point games during the 2020 NBA Playoffs despite failing to cross that threshold in any of the regular season games he played in the bubble. After struggling late in Boston's second-round series against Toronto and shooting just 32 percent in Game 1 against the Heat, he's shot 48.6 percent in his last two games. Lock him in as one of the top NBA DFS picks for Wednesday's Game 4 matchup. 

How to set your NBA DFS lineups for Sept. 23

McClure is also targeting another player who has a dream matchup on Wednesday. The stars are aligning for him to return 50, even 60 points on DraftKings and FanDuel. This pick could be the difference between winning your tournaments and cash games or going home with nothing. You can only see who it is here

So who are DFS pro Mike McClure's top picks for NBA DFS lineups on Wednesday? Visit SportsLine now to see the top NBA DFS picks and player pool from a professional DFS player who has almost $2 million in career winnings, and find out.