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The Detroit Pistons will take on the Denver Nuggets at 8 p.m. ET on Friday at Little Caesars Arena. Detroit is 20-50 overall and 13-21 at home, while Denver is 46-24 overall and 21-13 on the road. The Nuggets won the first meeting of the season on April 6, 134-119. 

Denver is favored by 9.5 points in the latest Pistons vs. Nuggets odds from William Hill Sportsbook, and the over-under is set at 220.5. Before entering any Nuggets vs. Pistons picks, you'll want to see the NBA predictions from the model at SportsLine.

The SportsLine Projection Model simulates every NBA game 10,000 times and has returned over $9,100 in profit on its top-rated NBA picks over the past two-plus seasons. The model is up over $1,100 on its top-rated picks this season and entered Week 21 of the 2020-21 NBA schedule on a stunning 99-64 roll on top-rated NBA picks against the spread dating back to last season. Anybody who has followed it has seen huge returns.

Now, the model has set its sights on Pistons vs. Nuggets. You can head to SportsLine to see its picks. Here are several NBA betting lines for Nuggets vs. Pistons:

  • Pistons vs. Nuggets spread: Pistons +9.5
  • Pistons vs. Nuggets over-under: 220.5 points
  • Pistons vs. Nuggets money line: Denver -500, Detroit +400  
Featured Game | Detroit Pistons vs. Denver Nuggets

What you need to know about the Pistons

On Tuesday, the Pistons lost to the Minnesota Timberwolves at home, 119-100. Detroit was down 86-65 at the end of the third quarter. Saben Lee had 22 points and five assists. The Pistons have lost 10 of their past 12 games.

Detroit is headed to its worst finish since the 1994 season. Isaiah Stewart (personal), Jerami Grant (knee), Frank Jackson (ankle), Wayne Ellington (calf), Cory Joseph (ankle) and Mason Plumlee (rest) are out for Friday's game. Hamidou Diallo (health and safety protocols) is questionable. 

What you need to know about the Nuggets

Denver strolled past Minnesota on Thursday, 114-103. Nikola Jokic posted a double-double on 31 points and 14 boards. Jokic leads the NBA with 59 double doubles this season. The Nuggets have wrapped up home-court advantage in the first round of the Western Conference playoffs. 

Denver is still one game behind the Clippers for the third seed with two games left to play. JaVale McGee had 12 points and 13 rebounds on Thursday. Michael Porter Jr. and Monte Morris were held out of the game against Minnesota. 

How to make Pistons vs. Nuggets picks

The model has simulated Pistons vs. Nuggets 10,000 times and the results are in. It is leaning under on the total, and it's also generated a point-spread pick that is hitting in almost 70 percent of simulations. You can only see the pick at SportsLine.

So who wins Pistons vs. Nuggets? And which side of the spread hits in almost 70 percent of simulations? Visit SportsLine now to see which side of the Pistons vs. Nuggets spread to jump on Thursday, all from the model that is on an incredible 99-64 roll.