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Get ready for a Southwest Division battle as the New Orleans Pelicans and the San Antonio Spurs face off at 8 p.m. ET on Saturday. San Antonio is 16-12 overall and 7-8 at home, while New Orleans is 14-18 overall and 5-11 on the road. The Spurs have won the last four games between the teams.

New Orleans is favored by 4.5 points in the latest Spurs vs. Pelicans odds from William Hill Sportsbook, and the over-under is set at 229. Before entering any Pelicans vs. Spurs picks, you'll want to see the NBA predictions from the model at SportsLine.

The SportsLine Projection Model simulates every NBA game 10,000 times, and it returned over $5,000 in profit on its top-rated NBA picks last season. The model is also up almost $8,700 on top-rated NBA picks over the past two-plus seasons. Dating back to last season, it enters Week 10 of the 2020-21 NBA schedule on a stunning 85-49 roll on top-rated NBA picks against the spread. Anybody who has followed it has seen huge returns.

Now, the model has set its sights on Spurs vs. Pelicans. You can head to SportsLine to see its picks. Here are several NBA betting lines for Spurs vs. Pelicans:

  • Spurs vs. Pelicans spread: Spurs +4.5
  • Spurs vs. Pelicans over-under: 229 points

What you need to know about the Spurs

The Spurs lost 102-99 to the Oklahoma City Thunder on Wednesday on a last-minute jumper from Oklahoma City's Luguentz Dort as the clock expired. It was the first game for San Antonio in 10 days because of four postponed games. The Spurs had won five of six prior to the postponements and loss to the Thunder.

Dejounte Murray had 27 points, nine rebounds and six assists versus OKC. DeMar Derozan (personal) and LaMarcus Aldridge (wrist) are questionable for Saturday's game. Derrick White, Rudy Gay and Keldon Johnson will be out due to health and safety protocols. 

What you need to know about the Pelicans

New Orleans took a 129-125 loss against the Milwaukee Bucks on Thursday. Zion Williamson had 34 points and six assists in addition to eight boards. The Pelicans totaled only nine assists against the Bucks. 

The Pelicans lost the first meeting of the season against the Spurs, 98-95, on Dec. 27. In that game, Brandon Ingram led New Orleans with 28 points, 11 rebounds and six assists.

How to make Spurs vs. Pelicans picks

The model has simulated Spurs vs. Pelicans 10,000 times and the results are in. The model is leaning over, and it's also generated a point-spread pick that is hitting in well over 50 percent of simulations. You can only see the pick at SportsLine.

So who wins Spurs vs. Pelicans? And which side of the spread hits in well over 50 percent of simulations? Visit SportsLine now to see which side of the Spurs vs. Pelicans spread to jump on Saturday, all from the model on an incredible 85-49 roll.