The Philadelphia 76ers take on the Milwaukee Bucks on the second night of a back-to-back set on Thursday. Philadelphia (39-19) hosted the Phoenix Suns on Wednesday, facing a challenging pair of games in only 24 hours. The Bucks (35-22) will aim to break a two-game losing streak in this Eastern Conference showdown. Seth Curry (hip), Tobias Harris (knee) and Ben Simmons (illness) missed Wednesday's game for Philadelphia and are all considered day-to-day. 

Tip-off is scheduled for 7 p.m. ET at Fiserv Forum in Milwaukee. The latest Bucks vs. Sixers odds from William Hill Sportsbook list Milwaukee as an eight-point favorite. The over-under for total points is set at 225.5. Before finalizing any Sixers vs. Bucks picks, be sure to see the NBA predictions and betting advice from SportsLine's proven computer model.

The SportsLine Projection Model simulates every NBA game 10,000 times, and it has returned over $9,200 in profit on its top-rated NBA picks over the past two-plus seasons. The model is up over $1,200 on its top-rated picks this season, and dating back to last year, it entered Week 18 of the 2020-21 NBA schedule on a stunning 96-60 roll on top-rated NBA picks against the spread. Anybody who has followed it has seen huge returns.

Now, the model has set its sights on Bucks vs. 76ers. You can head to SportsLine to see its picks. Now, here are several NBA odds and betting trends for 76ers vs. Bucks:

  • 76ers vs. Bucks spread: Bucks -8
  • 76ers vs. Bucks over-under: 225.5 points
  • 76ers vs. Bucks money line: Bucks -345, 76ers +285
  • PHL: The 76ers are 14-13-2 against the spread in 2020-21 road games
  • MIL: The Bucks are 13-15 against the spread in 2020-21 home games
Featured Game | Milwaukee Bucks vs. Philadelphia 76ers

Why the Sixers can cover

Philadelphia has notable strengths on both ends, including an unquestionably elite defense. The 76ers rank in the top five in overall defensive rating, with top-tier marks in shooting efficiency allowed and turnover creation rate. Philadelphia has a mild weakness in sending its opponents to the free throw line, but Milwaukee ranks 25th in the NBA in free throw creation offensively, mitigating some of the downside. 

The 76ers are also a potent defensive rebounding team, pulling down more than 76 percent of missed shots by their opponents. On the offensive side, Philadelphia leads the NBA in free throw creation rate, buoying its overall efficiency by keeping constant pressure on the rim. The 76ers turn the ball over more frequently than they would like, but Milwaukee's conservative defensive scheme leads to a turnover creation rate of only 12.8 percent, which ranks just 24th in the NBA.

Why the Bucks can cover

Milwaukee is one of the NBA's best teams, out-scoring opponents by 6.1 points per 100 possessions for the season. That overall success stems from remarkably impressive units on both ends of the floor. The Bucks are scoring 1.16 points per possession in 2020-21, ranking in the top five of the NBA, and that includes a top-three mark in shooting efficiency. They have few weaknesses offensively, with above-average metrics in offensive rebounding and ball security. 

On the opposite end, the Bucks lead the NBA in free throw rate allowed, and they are a top-five group in defensive rebounding and shooting efficiency allowed. Philadelphia turns the ball over on nearly 15 percent of possessions, and the Bucks can potentially benefit from that carelessness. Milwaukee also excels in specialized situations, ranking in the top three in both points in the paint allowed (43.2 per game) and fast break points allowed (10.5 per game).

How to make Bucks vs. Sixers picks

SportsLine's model is leaning over on the total, projecting the teams to combine for 226 points. The model also says one side of the spread hits well over 60 percent of the time. You can get that pick at SportsLine.

So who wins Bucks vs. Sixers? And which side of the spread hits well over 60 percent of the time? Visit SportsLine now to find out which side of the spread you need to jump on, all from the model that is on a roll on NBA picks.