Was among 15 semifinalists for the 2012 Thorpe Award and 20 quarterfinalists for the 2012 Lott Trophy. He made 2012 SI.com All-American honorable mention, All-Pac-12 second team, Phil Steele All-Pac-12 first team and CollegeFootballNews.com All-Pac-12 first team. He was USC's 11th 2-time Trojan captain and joined his father, Tim McDonald (USC's captain in 1986), as the only father-son captains in Trojan history. He was voted USC's Most Inspirational Player and was named the Defensive Perimeter Player of the Year. He was a Senior Bowl invitee.
He had 5 tackles (2 for a loss) with a deflection against Hawaii, added 6 stops against Syracuse, had 9 tackles and blocked a field goal attempt at Stanford and had 9 tackles, an interception and a deflection against California. He had a team-high 9 tackles at Utah, 9 tackles (including 1 for a loss) at Washington, 6 tackles at Colorado, a game-best 13 tackles (1.5 for losses) at Arizona and 10 tackles (0.5 for a loss) against Oregon. He had 7 tackles, an interception and returned a short kickoff 2 yards against Arizona State, 6 tackles (with a sack) and a deflection at UCLA and 10 tackles (0.5 for a loss) versus Notre Dame. He had 13 tackles against Georgia Tech.
He was one of 15 semifinalists for the 2011 Thorpe Award and one of 20 quarterfinalists for the Lott IMPACT Trophy. He made the 2011 Sporting News and Pro Football Weekly All-American first team (joining his father, Tim, as the first father-son All-American first teamers in USC history), the SI.com All-American second team and the Phil Steele All-American third team.He made the 2011 All-Pac-12 first team. He made the 2011 ESPN.com, CBSSports.com, CollegeFootballNews.com and Phil Steele All-Pac-12 first team. He won USC's 2011 Defensive Perimeter Player of the Year Award. He was a USC captain (joining his father, Tim, as the first father-son captains in Trojan history).
He had a team-best 8 tackles against Minnesota, then had 2 stops and a fumble recovery (to set up a USC TD) against Utah and 5 tackles against Syracuse. He had 6 tackles at Arizona State and then he had a pair of first quarter interceptions against Arizona (the first ended Nick Foles' streak of 210 passes without a pick dating to 2010) and he also had 6 tackles and a deflection to earn Lott IMPACT Trophy National Player of the Week and Thorpe Award National Defensive Back of the Week. He made 2 tackles (0.5 for a loss) at California, 5 tackles at Notre Dame and 5 tackles against Stanford (1 for a loss). He had 4 tackles while playing only the second half at Colorado (he was suspended for the first half by the Pac-12 for a hit in the Stanford game). He had 6 tackles against Washington and 8 tackles and blocked a punt at Oregon. Against UCLA, he had a game-best 10 tackles and had an interception (in the end zone with the Bruins threatening in the red zone) that he returned 25 yards and a deflection.
He had 4 stops with a deflection at Hawaii, then a game-best 14 tackles with an interception (in the end zone) and a deflection against Virginia, 7 tackles (with a sack) at Minnesota, 6 tackles (1 for a loss) and an interception that he ran back 20 yards at Washington State and a game-best 11 tackles against Washington. He added 4 tackles at Stanford, 3 tackles and an interception (to set up a USC TD) against California and 6 tackles (1 for a loss) and a deflection against Oregon.
He had a game-high 13 tackles and blocked a punt (he also partially blocked another punt and downed a punt at the ASU 4-yard line) against Arizona State to earn Pac-10 Defensive Player of the Week honors, a game-high 10 tackles against Arizona and a team-best 10 tackles with a deflection at Oregon State. He had a tackle against Notre Dame before spraining his shoulder early in the game (and sidelining him for the season finale at UCLA).
As a junior in 2007, he made Rivals.com Junior All-American second team, Cal-Hi Sports All-State Underclass first team, All-CIF Central Section and Fresno Bee All-Star. His father, Tim, was the head coach at Edison.
His brother, Tevin, is a sophomore cornerback at UCLA. His initials stand for Tim Jr. He and 15 of his USC teammates spent 5 days in Haiti in the spring of 2012 building homes and assisting those in need.