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The Detroit Lions will hope to go home with a win after their traditional Thanksgiving Day game when they host the Houston Texans. The Lions (4-6) have lost three straight on Thanksgiving, but they face a team in a similar position, with both teams hurting at running back and struggling on defense. It should be a battle between quarterbacks, with Texans young gun DeShaun Watson trying to outduel Lions veteran Matthew Stafford. Houston (3-7) beat New England last week, while the Lions were shut out by the Panthers.

Kickoff for Lions vs. Texans on NFL Thanksgiving Day 2020 is scheduled for 12:30 p.m. ET. William Hill Sportsbook lists the Texans as three-point favorites in its latest Texans vs. Lions odds, with the over-under for total points scored set at 51.5. Before making any Lions vs. Texans picks or NFL predictions, check out what SportsLine's resident Lions expert, R.J White, has to say

CBS Sports' NFL editor, White enters Week 11 on a sizzling 31-22 run. It's no surprise, as White twice has cashed huge in the world's most prestigious football handicapping competition, the Las Vegas SuperContest. 

Moreover, White has a particularly keen eye for the Lions. In fact, he is a stunning 39-22 in his last 61 NFL picks involving Detroit. Anyone who has followed his NFL picks is way up. 

Now, White has broken down Texans vs. Lions from every possible angle. You can head to SportsLine to see the picks. Here are the latest NFL odds and trends for Lions vs. Texans:

  • Texans vs. Lions spread: Houston -3
  • Texans vs. Lions over-under: 51.5
  • Texans vs. Lions money line: Houston -160, Detroit +140
  • HOU: WR Will Fuller has at least five receptions in four of the last five games
  • DET: TE T.J. Hockenson has at least four catches in seven games this season

Why the Texans can cover

Quarterback Deshaun Watson was in vintage form in last Sunday's win against New England and now faces a Lions team that is 3-7 against the spread in its last 10 home games. He threw for 344 yards and two TDs and also ran for 36 and a score. The fourth-year pro has completed 68.8 percent of his passes for 2,883 yards and 20 touchdowns and has plenty of weapons to do damage. Wide receivers Will Fuller and Brandin Cooks share the team lead with 47 catches, and Fuller averages 15.1 yards per catch.

The Texans' defense has the ability to wreak havoc, and the Lions are 4-11 against the spread in their last 15 games as underdogs. Three-time Defensive Player of the Year J.J. Watt brings a swagger into the unit when he is healthy, and he has four sacks and batted down seven passes.

With Adrian Peterson the top healthy rusher and averaging just 3.7 yards per carry for the Lions, the Texans' defense can focus on Stafford, who has been sacked 27 times and thrown seven interceptions.

Why the Lions can cover

Detroit is 6-2 against the spread in its last eight Thanksgiving Day NFL games, and the Texans' defense is second-worst in the league, allowing 411.7 yards per game. Houston allows 139.0 rushing yards per game and has allowed 17 rushing TDs, the most in the NFL. The Lions are banged up at running back, but Adrian Peterson and Kerryon Johnson can break runs if they find holes. Peterson has rushed for 389 yards, while Johnson was the team's top rusher last season.

Stafford is in his 12th season and has consistently put up numbers for the Lions, who are 4-3 against the spread in non-division games this season. He has thrown for 2,591 yards and 17 touchdowns and has counted on Marvin Jones (37 catches for 455 yards) and tight end T.J. Hockenson (team-high 40 for 441 yards) with Kenny Golladay (hip) out.

How to make Texans vs. Lions picks

White has analyzed this matchup from all sides and is leaning Over on the total. He also has discovered a critical X-factor that has him jumping all over one side of the spread. He's only sharing it here

So who wins Texans vs. Lions on Thanksgiving Day? And what critical X-factor makes one side of the spread a must-back? Visit SportsLine right now to find out which side of the Lions vs. Texans spread you should be all over Thursday, all from the expert who is 39-22 in his last 61 picks involving Detroit.