The greatest quarterback of all-time, Tom Brady, and the NFL's reigning 25-year-old superstar, Patrick Mahomes, will square off on Sunday on the biggest stage of them all, Super Bowl 55 between the Tampa Bay Buccaneers and Kansas City Chiefs. Either Tampa Bay's Brady, 43, will add to his record six Super Bowl titles as his career enters its final stages or Kansas City's Mahomes will continue his record-setting ascent with his second Super Bowl ring in just his fourth season. Sunday's game between the Chiefs (16-2) and Buccaneers (14-5) will be the fifth meeting between the quarterbacks, who have split the first four meetings 2-2.

Kickoff from Raymond James Stadium is scheduled for 6:30 p.m. ET. William Hill Sportsbook lists Kansas City as a three-point favorite in the latest 2021 Super Bowl odds, while the over-under is 56, down one from the opener. Before you make any Super Bowl picks or Buccaneers vs. Chiefs picks, you have to see what Tampa Bay expert R.J. White has to say. 

CBS Sports' Fantasy and gambling editor, White is currently SportsLine's No. 1 NFL expert, entering the title game on an 80-58 run on all NFL picks, returning more than $1,500 during that span. It's no surprise, as White has cashed huge twice in the world's most prestigious football handicapping competition, the Las Vegas SuperContest. 

In addition, White is an amazing 24-14 on NFL picks against-the-spread involving the Bucs. Anyone who has followed him is way up. 

Now, White has broken down the Super Bowl 2021 odds from every angle. You can head to SportsLine to see the picks. Here are the NFL odds and trends for Buccaneers vs. Chiefs:

2021 Super Bowl spread: Kansas City -3
2021 Super Bowl over-under: 56
2021 Super Bowl money line: Kansas City -165, Tampa Bay +145
KC: TE Travis Kelce has at least seven catches in 10 straight games
TB: QB Tom Brady has thrown for at least 250 yards in 12 games this season

Why the Chiefs can cover

The Bucs rank 21st against the pass and give up the second-most completions per game in the league (26.6). The Chiefs, who are 4-1 against the spread in their last five playoff games, piled up 543 yards in a 27-24 victory against the Bucs in Week 12. Quarterback Patrick Mahomes threw for 462 and three TDs in that game, while wide receiver Tyreek Hill had 203 yards and two scores in the first quarter.

If the Bucs clamp down on Hill, Mahomes will simply turn to tight end Travis Kelce, who has 126 catches for 1,640 yards in 18 games this season.

Defensively, ends Frank Clark and Tanoh Kpassagnon will join Chris Jones in giving Brady a tough time. The three have combined for 17.5 sacks this season, while Mathieu has picked off seven passes, including a game-changer in the AFC championship. 

Why the Buccaneers can cover

Tampa Bay has a defense that can cause major issues for Kansas City and its reworked offensive line. Jason Pierre-Paul led the team and ranked 11th in the league in sacks during the regular season with 9.5, while Devin White and Shaquil Barrett added nine and eight, respectively. Led by those three, the Buccaneers had 48 sacks during the regular season, which was tied for the fourth most in the league.

On Super Bowl Sunday, they'll go up against a Chiefs offensive line that has been forced to play musical chairs with the season-ending injury to left tackle Eric Fisher. The line will have three positions -- left tackle, right tackle and right guard -- with different starters from the AFC Championship Game.

In addition, Tampa Bay's offense has made significant strides since losing to Kansas City in Week 12. In the Buccaneers' last seven games, they have scored 34.3 points per contest and gone 7-0. That is a substantial increase from the first 12 weeks of the season, when they scored 28.7 points per game and went 7-5. 

How to make 2021 Super Bowl picks

White has analyzed this matchup from all sides and is leaning Under on the total. He also has discovered a critical X-factor that has him jumping all over one side of the spread. He's only sharing it here. 

So who wins Chiefs vs. Buccaneers in the 2021 Super Bowl? And what critical X-factor makes one side of the spread a must-back? Visit SportsLine right now to find out which side of the Buccaneers vs. Chiefs spread you should be all over, all from the expert who is a 24-14 on picks involving Tampa Bay.