Who's Playing

Seattle @ San Francisco

Current Records: Seattle 1-2; San Francisco 2-1

What to Know

The San Francisco 49ers are 2-8 against the Seattle Seahawks since September of 2016, but they'll have a chance to close the gap a little bit Sunday. The 49ers and Seattle will face off in an NFC West battle at 4:05 p.m. ET at Levi's Stadium. San Francisco is expected to win -- but not by much -- so they will need to come into the game prepared for a fight.

San Francisco was hampered by 86 penalty yards against the Green Bay Packers last week. San Francisco fell just short of Green Bay by a score of 30-28. No one had a standout game offensively for San Francisco, but they got scores from a handful of players including FB Kyle Juszczyk, QB Trey Lance, and WR Brandon Aiyuk. QB Jimmy Garoppolo ended up with a passer rating of 128.

Meanwhile, the Seahawks were first on the board but had to settle for second at the end of their matchup against the Minnesota Vikings last week. Seattle fell to Minnesota 30-17. Despite the loss, Seattle had strong showings from RB Chris Carson, who punched in one rushing touchdown, and WR DK Metcalf, who caught six passes for one TD and 107 yards.

With the two teams each stumbling in off of a loss, both will be hungry for the win. Check back to see which squad is able to work their way into the win column.

How To Watch

  • When: Sunday at 4:05 p.m. ET
  • Where: Levi's Stadium -- Santa Clara, California
  • TV: FOX
  • Online streaming: fuboTV (Try for free. Regional restrictions may apply.)
  • Follow: CBS Sports App
  • Ticket Cost: $85.00


The 49ers are a slight 2.5-point favorite against the Seahawks, according to the latest NFL odds.

The oddsmakers had a good feel for the line for this one, as the game opened with the 49ers as a 3-point favorite.

Over/Under: -111

See NFL picks for every single game, including this one, from SportsLine's advanced computer model. Get picks now.

Series History

Seattle have won ten out of their last 12 games against San Francisco.

  • Jan 03, 2021 - Seattle 26 vs. San Francisco 23
  • Nov 01, 2020 - Seattle 37 vs. San Francisco 27
  • Dec 29, 2019 - San Francisco 26 vs. Seattle 21
  • Nov 11, 2019 - Seattle 27 vs. San Francisco 24
  • Dec 16, 2018 - San Francisco 26 vs. Seattle 23
  • Dec 02, 2018 - Seattle 43 vs. San Francisco 16
  • Nov 26, 2017 - Seattle 24 vs. San Francisco 13
  • Sep 17, 2017 - Seattle 12 vs. San Francisco 9
  • Jan 01, 2017 - Seattle 25 vs. San Francisco 23
  • Sep 25, 2016 - Seattle 37 vs. San Francisco 18
  • Nov 22, 2015 - Seattle 29 vs. San Francisco 13
  • Oct 22, 2015 - Seattle 20 vs. San Francisco 3