The Chicago Bears did not defend the pass well in their season-opening 34-14 loss to the Los Angeles Rams, allowing Matthew Stafford to throw for 321 yards and three touchdowns. They now are faced with the task of stopping another dangerous passer in Joe Burrow when they host the Cincinnati Bengals on Sunday. The 2019 Heisman Trophy winner, Burrow racked up 261 passing yards and two TDs in the Bengals' 27-24 overtime victory over the Minnesota Vikings in Week 1. Before suffering a season-ending knee injury in Week 11 of his 2020 rookie season, Burrow recorded five 300-yard performances and threw two or more scoring passes on four occasions.

Kickoff from Soldier Field is set for 1 p.m. ET. Chicago is a 1.5-point favorite in the latest Bears vs. Bengals odds from Caesars Sportsbook, while the over-under for total points scored is 44.5. Before locking in any Bengals vs. Bears picks, make sure you check out the latest NFL predictions and analysis from SportsLine's proven computer projection model.

The model, which simulates every NFL game 10,000 times, is up almost $7,900 for $100 players on top-rated NFL picks since its inception six-plus years ago. It went a sizzling 24-14 on top-rated NFL picks last season, returning more than $800. The model also enters Week 2 of the 2021 season on an incredible 121-79 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the Top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

Now, the model has set its sights on Bears vs. Bengals on Sunday and just revealed its picks and predictions. You can visit SportsLine now to see the model's Bears vs. Bengals picks. Here are the NFL odds and betting trends for Bengals vs. Bears:

  • Bears vs. Bengals spread: Chicago -1.5 
  • Bears vs. Bengals over-under: 44.5 points 
  • Bears vs. Bengals money line: Chicago -125, Cincinnati +105
  • CHI: Bears are 1-7 against the spread in their last eight games as home favorites 
  • CIN: Bengals are 6-2 ATS in their last eight contests versus teams with losing records
Featured Game | Chicago Bears vs. Cincinnati Bengals

Why the Bears can cover

Chicago registered just one sack against the Rams in Week 1, but will face a less-than-stellar offensive line on Sunday. The Bengals were one of the worst at protecting their quarterback last season, finishing tied for fifth in most sacks allowed with 48. They didn't show any improvement in their season opener, as Minnesota sacked Burrow five times.

Khalil Mack was not a factor in the loss at Los Angeles last Sunday, but is one of the most feared pass rushers in the NFL. The 30-year-old linebacker has led the Bears in sacks in each of his first three seasons since being acquired from the then-Oakland Raiders prior to the 2018 campaign, registering a total of 30 in that span. Mack has amassed 70.5 sacks in 111 NFL contests, notching at least 8.5 each of the last six years and reaching double-digits four times during that stretch.

Why the Bengals can cover

Joe Burrow made his first appearance since tearing the ACL and MCL in his left knee in Week 11 of his 2020 rookie season and threw for 261 yards and two touchdowns in Cincinnati's season-opener. The first overall pick in the 2020 NFL Draft, Burrow enjoyed a successful reunion with former LSU teammate Ja'Marr Chase, who was drafted fifth overall this year. The 21-year-old Chase caught five of the seven passes Burrow threw his way for 101 yards, 50 of which came on a scoring toss just before halftime.

The 24-year-old Burrow has another young target at his disposal in Tee Higgins, a second-round pick in 2020. A 22-year-old receiver out of Clemson, Higgins had four catches for 58 yards and a touchdown in the opener. He had a strong rookie campaign last year, leading the Bengals with 908 yards and six TDs on 67 receptions.

How to make Bears vs. Bengals picks

SportsLine's model is leaning over on the point total. In fact, it says Burrow and Dalton combine to throw for more than three touchdowns. It also says one side of the spread cashes in nearly 60 percent of simulations. You can only get the model's Bears vs. Bengals pick at SportsLine.

So who wins Bengals vs. Bears on Sunday? And which side of the spread hits almost 60 percent of the time? Visit SportsLine now to see which side of the Bears vs. Bengals spread to back on Sunday, all from the advanced model that is up almost $7,900 on its top-rated NFL picks, and find out.