The Detroit Lions will take on the Arizona Cardinals at 1 p.m. ET on Sunday at Ford Field. Detroit is 1-11-1 overall and 1-5 at home, while Arizona is 10-3 overall and 7-0 on the road. The Cardinals are 3-3 since starting the season with a 7-0 record. The Lions have lost three of their last four games.
The Lions have won three of the last four games between the teams. Arizona is favored by 12.5 points in the latest Lions vs. Cardinals odds from Caesars Sportsbook, and the over-under is set at 47.5. Before entering any Cardinals vs. Lions picks, you'll want to see the NFL predictions from the model at SportsLine.
The model, which simulates every NFL game 10,000 times, is up almost $7,000 for $100 players on top-rated NFL picks since its inception six-plus years ago. The model enters Week 15 of the 2021 season on an incredible 132-96 run on top-rated NFL picks that dates back to the 2017 season.
The model also ranked in the top 10 on NFLPickWatch four of the past five years on straight-up NFL picks and beat more than 94 percent of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.
Now, the model has set its sights on Lions vs. Cardinals. You can head to SportsLine to see its picks. Here are several NFL betting lines for Cardinals vs. Lions:
- Lions vs. Cardinals spread: Cardinals -12.5
- Lions vs. Cardinals over-under: 47.5 points
What you need to know about the Lions
The Lions took a 38-10 loss against the Denver Broncos last Sunday. Detroit was shut out in three of four quarters. The Lions were outgained 135 to minus-1 in the first quarter. Practice squad call-up Craig Reynolds rushed for 83 yards on 11 carries.
T.J. Hockenson (hand) is out for Week 15. D'Andre Swift (shoulder) and Josh Reynolds (though) are listed as questionable. Jamaal Williams and Tracy Walker are among the players on the reserve/COVID-19 list. Seven players were on the list in the loss to Denver last week.
What you need to know about the Cardinals
The Cardinals took a 30-23 hit to the loss column from the Rams on Monday. Kyler Murray threw two interceptions that led to Los Angeles TDs and was sacked four times without throwing a TD pass. He threw for 383 yards and rushed for 61. A.J. Green caught seven passes for 102 yards and James Conner had nine receptions for 94 yards while rushing for two TDs.
Conner (ankle) is questionable for Week 15. DeAndre Hopkins (knee surgery) is out indefinitely. Rodney Hudson is on the reserve/COVID-19 list. Justin Pugh (calf) is questionable.
How to make Lions vs. Cardinals picks
The model is leaning over on the total, and it's also generated a point-spread pick that is hitting in well over 50 percent of simulations. You can only see the pick at SportsLine.
So who wins Lions vs. Cardinals? And which side of the spread hits well over 50 percent of the time? Visit SportsLine right now to see which side of the spread you need to jump on, all from the computer model that has crushed its NFL picks.
