The Philadelphia Eagles will try to book the fourth trip to the Super Bowl in franchise history when they host the San Francisco 49ers in the 2023 NFC Championship Game on Sunday. Philadelphia (15-3), which is 3-4 in conference championship games, lost its first two Super Bowl appearances before defeating New England in 2017 to capture its elusive first NFL title since 1960. The 49ers (15-4) are playing in the NFC Championship Game for the third time in four years and hoping to advance to their eighth Super Bowl, which would tie them with Pittsburgh, Dallas and Denver for second on the all-time list.

Kickoff from Lincoln Financial Field is set for 3 p.m. ET. Philadelphia is a 2.5-point favorite in the latest Eagles vs. 49ers odds from Caesars Sportsbook, while the over/under for total points scored is 45.5. Before locking in any 49ers vs. Eagles picks, make sure you see the latest NFL predictions and betting advice from SportsLine's proven projection model.

The model, which simulates every NFL game 10,000 times, is up well over $7,000 for $100 players on top-rated NFL picks since its inception. The model enters the AFC Championship and NFC Championship of the 2023 NFL playoffs on an incredible 162-113 run on top-rated NFL picks that dates back to the 2017 season. It also is on a 16-6 roll on top-rated NFL picks since Week 7 of this season.

The model ranked in the Top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick'em players four times during that span. Anyone who has followed it is way up.

Now, the model has set its sights on Eagles vs. 49ers and just locked in its picks and NFC Championship Game predictions. You can head to SportsLine now to see the model's picks. Here are the NFL odds from Caesars Sportsbook and trends for 49ers vs. Eagles:

  • Eagles vs. 49ers spread: Philadelphia -2.5 
  • Eagles vs. 49ers over/under: 45.5 points 
  • Eagles vs. 49ers money line: Philadelphia -145, San Francisco +122 
  • PHI: Eagles are 6-2 against the spread in their last eight playoff games 
  • SF: 49ers are 9-1 ATS in their last 10 contests following a straight-up victory 
  • Eagles vs. 49ers picks: See picks here
Featured Game | Philadelphia Eagles vs. San Francisco 49ers

Why the Eagles can cover

Philadelphia is perhaps the most well-rounded team in the NFL, as it ranked second in total defense (301.5 yards allowed) and third in total offense (389.1 yards) during the regular season. The team was fifth in the league in rushing (147.6 yards) and is coming off a monster performance in its 38-7 triumph over the New York Giants in the Divisional Round, as it racked up 268 yards on the ground, the second-most in franchise playoff history. The Eagles displayed their depth in the win as Kenneth Gainwell, who was third on the team in rushing this campaign with 240 yards on 53 carries, ran 12 times for 112 yards and a touchdown.

Running back Miles Sanders posted his first career 1,000-yard season and was fifth in the NFL with 1,269, while quarterback Jalen Hurts gained 760 yards and recorded 13 rushing TDs to finish tied for second in the league. Philadelphia also had two 1,000-yard receivers in a season for the first time in franchise history after A.J. Brown set the single-season team record with 1,496 yards on 88 catches, while DeVonta Smith registered 1,196 on 95 receptions. The Eagles were first in the NFL with 70 sacks, finishing two shy of the league record set in 1984 by Chicago, and notched five against the Giants while safety C.J. Gardner-Johnson led the league with a career-high six interceptions. See which team to pick here.

Why the 49ers can cover

Many still look at quarterback Brock Purdy's lack of experience and question whether he can handle the pressure of the NFL playoffs 2023, but he already has more postseason wins under his belt than Philadelphia counterpart Jalen Hurts. The 23-year-old Purdy, who was the last pick in the 2022 NFL Draft, stepped in for an injured Jimmy Garoppolo in Week 13 and has led San Francisco to eight consecutive victories. The rookie has completed 62.7% of his pass attempts in the 2023 NFL playoffs for 546 yards and three touchdowns without an interception.

Wideout Deebo Samuel has been Purdy's top target this postseason, making 10 catches for 178 yards and a TD. Tight end George Kittle has seven receptions for 132 yards, while running backs Christian McCaffrey and Elijah Mitchell have each hauled in a scoring pass. In Purdy's seven starts, Kittle has made 29 catches for 425 yards and seven of his 11 touchdowns. See which team to pick here.

How to make Eagles vs. 49ers picks

SportsLine's model is leaning Under the point total, calling for 41 combined points. The model also says one side of the spread cashes in well over 50% of simulations. You can only see the model's NFL picks at SportsLine.

So who wins 49ers vs. Eagles in the NFC Championship Game 2023? And which side of the spread cashes well over 50% of the time? Visit SportsLine now to see which side of the 49ers vs. Eagles spread to be all over on Sunday, all from the advanced model that is up well over $7,000 on its top-rated NFL picks, and find out.