The Seattle Seahawks' defense will try to build confidence against a struggling offense when they visit Lincoln Financial Field for a Monday Night Football matchup with the Philadelphia Eagles. Seattle (7-3) is giving up the most yardage in the league, but quarterback Russell Wilson has willed the team to victories. Now, safety Jamal Adams and company will face an offense from Philadelphia (3-6-1) that scores just 22 points per game and is led by quarterback Carson Wentz, who leads the league with 14 interceptions.

Kickoff is scheduled for 8:15 p.m. ET at Lincoln Financial Field. William Hill Sportsbook lists Seattle as a 6.5-point favorite in its latest Eagles vs. Seahawks odds, while the over-under for total points scored is 49. Before making any Seahawks vs. Eagles picks or NFL predictions, be sure to check out the NFL predictions from the SportsLine Projection Model

The model, which simulates every NFL game 10,000 times, is up more than $7,800 for $100 players on top-rated NFL picks since its inception five-plus years ago. It is a sizzling 19-10 on top-rated NFL picks this season, returning almost $800. The model also enters Week 12 on an incredible 115-75 run on top-rated NFL picks that dates back to the 2017 season. 

The model ranked in the Top 10 on NFLPickWatch three of the past four years on straight-up NFL picks and beat more than 95 percent of CBS Sports office pool players three times during that span. Anyone who has followed it is way up. 

Now, the model has broken down Eagles vs. Seahawks. You can head to SportsLine to see the picks. Here are the NFL odds and trends for Eagles vs. Seahawks:

  • Eagles vs. Seahawks spread: Seattle -6.5
  • Eagles vs. Seahawks over-under: 49
  • Eagles vs. Seahawks money line: Seattle -280, Philadelphia +240
  • SEA: WR DK Metcalf has at least 90 receiving yards in seven games
  • PHI: RBs Miles Sanders and Boston Scott have combined for 238 yards over the past two games

Why the Seahawks can cover

Including the playoffs, Seattle is 6-0 against the Eagles under head coach Pete Carroll, winning by at least eight points and covering the spread each time. Adams will get plenty of opportunities to make plays against Wentz, who has turned the ball over 18 times and been sacked a league-high 40 times.

Adams leads the team with 5.5 sacks, and the addition of Carlos Dunlap has helped. The former Bengal was acquired in trade last month and has 3.5 sacks in three games with Seattle.

Wilson is 28-8-1 straight-up in primetime starts and is second in the league in passing yards with 2,986. He leads the NFL with 30 TD passes, with 17 of those going to top-flight receivers DK Metcalf (862 yards) and Tyler Lockett (748). Wilson also has a team-high 367 rushing yards. Running back Chris Carson, who rushed for 323 yards (4.9 per carry) in six games, should return on Monday Night Football.

Why the Eagles can cover

Philly is 21-19 against the spread at home since 2016, and the defense can get after the quarterback. The Eagles are second in the league with 34 sacks and pressure the quarterback on 25.5 percent of dropbacks. Wilson has been sacked 33 times and has 10 interceptions, so Brandon Graham (seven sacks), Fletcher Cox (4.5) and Derek Barnett (4.5) could be major factors.

Eagles quarterback Carson Wentz is 12-6 straight-up in primetime games and faces a Seattle defense that allows 434.9 total yards and 343.7 through the air per game. Seattle's front is not dangerous, with no linemen topping 3.5 sacks, so he should have time to operate.

How to make Eagles vs. Seahawks picks

SportsLine's model is leaning Under on the total, with the model saying the teams will combine for four turnovers. It also says one side of the spread is hitting well over 50 percent of the time. You can only get the pick at SportsLine

So who wins Seahawks vs. Eagles on Monday Night Football? And which side of the spread cashes well over 50 percent of the time? Visit SportsLine right now to see which side of the Seahawks vs. Eagles spread to back, all from the advanced model on a 115-75 run on its top-rated NFL picks.