The Philadelphia Eagles came into the season with high expectations, but currently have just one win. They'll hope a new chapter starts on Thursday Night Football against the New York Giants. Philadelphia (1-4-1) has been hit hard by injuries and quarterback Carson Wentz has been hit hard often, but the NFC East is still wide open. In fact, a second victory would equal first-place Dallas heading into the weekend. New York (1-5) got its first win in Week 6, but the 20-19 victory against Washington was a sloppy affair.

Philadelphia is a five-point favorite in the latest Giants vs. Eagles odds from William Hill, down from an open of 6.5, while the over-under is 44.5. Before locking in any Eagles vs. Giants picks, make sure you see the latest Thursday Night Football predictions from SportsLine's proven projection model

The model, which simulates every NFL game 10,000 times, is up over $7,800 for $100 players on top-rated NFL picks since its inception five-plus years ago. It's off to a strong 14-6 roll on top-rated NFL picks this season. The model also enters Week 7 on an incredible 110-71 run on top-rated NFL picks that dates back to the 2017 season.

The model ranked in the Top 10 on NFLPickWatch in three of the past four years on straight-up NFL picks and beat more than 95 percent of CBS Sports office pool players three times during that span. Anyone who has followed it is way up.

Now, the model has set its sights on Eagles vs. Giants. You can visit SportsLine now to see the picks. Here are the NFL odds from William Hill and trends for Giants vs. Eagles:

  • Giants vs. Eagles spread: Eagles -5
  • Giants vs. Eagles over-under: 44.5 points
  • Giants vs. Eagles money line: Giants +205, Eagles -245
  • NYG: 12th in the league in yards allowed at 342 per game
  • PHI: 12th in rushing at 122.3 yards per game

Why the Eagles can cover

Philly is 5-0 against the spread in its past five Thursday games, while the Giants have failed to cover in four straight on the shorter week. The defense should be able to make plays against a struggling New York offense, which has turned the ball over 10 times and yielded 17 sacks. The defense ranks 17th in total yards allowed (355.2) and 12th in passing (229.7), while the Giants are tied for last in total offense (275.3) and 30th in passing (187.5). 

Brandon Graham has five sacks for the Eagles, who are 11-5 against the spread in their last 16 games in October. Safeties Rodney McCloud and Jalen Mills lead a secondary that could give Giants quarterback Daniel Jones (six INTs) confusing looks. The bright spot on offense has been receiver Travis Fulgham, who has 248 receiving yards over the past three games.

Why the Giants can cover

New York enters this matchup with momentum after picking up its first win of the season last week against Washington. The Giants failed to cover as 1.5-point favorites in that matchup, but did stay within the spread the prior two weeks at +7 against the Cowboys and +13 against the Rams.

Despite their overall struggles, the Giants have been tough to blow out all season, as they've lost by more than 10 points just once.

The Giants are also getting healthier at receiver. Sterling Shepard (toe) has a chance to return to action on Thursday. He'll join Darius Slayton, who returned from a foot injury last week, to give quarterback Daniel Jones more options in the passing game. Running back Devonta Freeman is also settling in as a replacement for Saquon Barkley, who is out for the year with a torn ACL. The former Pro Bowl back in Atlanta scored a touchdown in Week 5 and saw a season-high 19 touches in Week 6.

How to make Giants vs. Eagles picks

SportsLine's model is leaning over on the total. In fact, it's calling for 47 total points. It has also generated an against-the-spread pick that cashes in more than 50 percent of simulations. You can only get the pick at SportsLine

So who wins Eagles vs. Giants on Thursday Night Football? And which side of the spread hits over 50 percent the time? Visit SportsLine now to see which side of the Eagles vs. Giants spread to jump on, all from the advanced model that is up more than $7,800 on its top-rated NFL picks, and find out.