NFL DFS for Chiefs vs. Chargers: Top DraftKings, FanDuel daily Fantasy football picks, lineups for Week 11

The Week 11 NFL schedule concludes with Chiefs vs. Chargers on Monday Night Football. Kickoff is at 8:15 p.m. ET from Estadio Azteca in Mexico City. It's one the most anticipated single-game slates of the year for NFL DFS players, as Patrick Mahomes, Tyreek Hill and Travis Kelce lead the NFL's third-ranked offense against Philip Rivers, Melvin Gordon and the Chargers in a game with a sky-high over-under of 53 points. Which of those potential NFL DFS picks for Monday Night Football should be part of your optimal NFL DFS strategy for tournaments like the $1.55M South of the Border Showdown on DraftKings or the $800K NFL Monday Night Special on FanDuel? Before setting your Chiefs vs. Chargers DFS lineups, be sure to see the latest NFL DFS advice from SportsLine's Mike McClure, who has won almost $2 million in his career.

McClure is also a predictive data engineer at SportsLine who uses a powerful prediction model that simulates every minute of every game 10,000 times, taking factors like matchups, statistical trends and injuries into account. This allows him to find the best NFL DFS values and create optimal lineups that he shares only over at SportsLine. They're a must-see for any NFL DFS player.

McClure had eye-popping results during the 2018 NFL season, cashing in the top 5 percent of tournaments on FanDuel and DraftKings multiple times. His optimal lineups cashed as high as the top 0.1 percent on FanDuel and as high as the top 1 percent on DraftKings.

He's rolling through 2019 as well, including a strong 3x return on DraftKings in the Week 3 main slate. On Sunday of Week 5, his optimal lineup finished in the top 1 percent of tournaments on DraftKings, with his four core players -- Deshaun Watson, Michael Thomas, Christian McCaffrey and Will Fuller -- combining for a whopping 196.34 points, enough to cash in tournaments by themselves. He followed that up by cashing his FanDuel and DraftKings lineups on Sunday Night Football and Monday Night Football in Week 6 and then cashed everywhere on his SNF lineups yet again in Week 7. He continued his roll with wins on both sites on the main slate, SNF and MNF in Week 8, and then followed that up with huge 5x returns on his optimal lineups on both sites in Week 9. Anyone who has been following him has seen huge returns.

Now, he has turned his attention to Chiefs vs. Chargers on Monday Night Football and locked in his top daily Fantasy football picks. You can only see them by heading to SportsLine.

For Monday Night Football DFS, we can tell you McClure is banking on Rivers. The 37-year old veteran has seen his season-long numbers (2,816 yards, 14 touchdowns, 10 INTs) slow slightly, but he's in a prime spot this week since he draws an enticing matchup against the Chiefs, a defense that has given up the 10th-most Fantasy points to opposing quarterbacks this season. 

Daily Fantasy players who have targeted quarterbacks playing the Chiefs have seen plenty of returns, with Ryan Tannehill going off for almost 4x value on DraftKings against KC, Kirk Cousins hitting 3x, and Aaron Rodgers exploding for well over 4x, so confidently lock in Rivers as one of the top Chargers vs. Chiefs DFS picks for Monday Night Football. 

Part of McClure's optimal NFL DFS strategy also includes rostering Kelce, who leads all tight ends in receiving yards per game (74.1) on the season. The Chargers have been tough against tight ends, giving up the seventh-fewest points to that position. But McClure's model still loves the value of Kelce (56-741-1) because he's proven be largely matchup-proof. In fact, he's piled up strong numbers in recent weeks against top-10 scoring defenses like the Titans (7-75-1) and the Vikings (7-62). 

McClure is also targeting a player who could go off for massive numbers on Monday Night Football in Mexico City because of a dream matchup. This pick could be the difference between winning your tournaments and cash games or going home with nothing.

So who is DFS pro Mike McClure putting in his optimal NFL DFS lineup on Monday night? Visit SportsLine now to see the full optimal tournament lineups for Chiefs vs. Chargers from a professional DFS player who has almost $2 million in career winnings, and find out.

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