NFL DFS for Monday Night Football, Week 12: Optimal DraftKings, FanDuel daily fantasy football picks and lineups

NFL DFS players get a final shot at Week 12 when the Tennessee Titans take on the Houston Texans at NRG Stadium on Monday Night Football. Kickoff is at 8:15 p.m. ET. This matchup features a pair of top-five scoring defenses, so points and yardage could be tough to come by. That means there are plenty of tough decisions to make before setting any Monday Night Football DFS lineups for tournaments like the $1M Monday Night Showdown on DraftKings or the $650K Monday Night Special on FanDuel. Before locking in picks for any tournaments or cash games, be sure to check out the top Texans vs. Titans NFL DFS picks and advice from SportsLine's Mike McClure. He's a professional DFS player who has won almost $2M in his career.

McClure uses a powerful prediction model that simulates every snap of every game 10,000 times, taking factors like matchups, statistical trends and injuries into account. This allows him to find the best NFL DFS values and create optimal lineups that he shares only over at SportsLine. They're a must-see for any NFL DFS player. 

McClure is rolling through the 2018 season thanks to some spot-on picks. In Week 1, his optimal NFL DFS lineups finished in the top 3 percent of tournaments on DraftKings and the top 1 percent of tournaments on FanDuel. In Week 4, he finished in the top 2 percent on DraftKings and top 6 percent on FanDuel. In Week 5, his lineups cashed with ease on both sites. In Week 8, his followers saw massive returns, with his DraftKings lineup finishing in the top 1 percent of all tournaments, while his Week 9 lineup cashed with ease on FanDuel. He cashed yet again on both sites in Week 10, and then his Sunday optimal lineup on FanDuel returned almost 3x last week. Anyone who has followed him is way up. 

For Monday night's single-game slate of Texans vs. Titans, we can tell you McClure is banking on Houston wide receiver DeAndre Hopkins

Listed as questionable (foot) earlier in the week, Hopkins shed his injury designation over the weekend and appears to be close to 100 percent. A top-10 receiver in the league in yardage (950) and touchdowns (8) this season, Hopkins comes into Monday Night Football with at least one score in five straight games. 

Hopkins has torched the Titans in recent matchups, posting stat lines of 6-110-1, 10-107-1 and 8-80 the last three times these teams have met. Quarterback Deshaun Watson has targeted him a whopping 37 times against Tennessee over the last two seasons. 

McClure's NFL DFS advice for Monday Night Football also includes rostering Tennessee's No. 1 receiver, Corey Davis

Davis can be a boom-or-bust option, but with 10 targets in each of the last two full games quarterback Marcus Mariota has played in, his ceiling is sky-high. And when Davis is on, he can put up eye-popping numbers like the 7-125-1 line he recorded against the Patriots or the 9-161-1 effort against the Eagles

McClure is also targeting a player who could go off for massive numbers on Monday Night Football because of a dream matchup. This pick could be the difference between winning your tournaments and cash games or going home with nothing. 

So who is DFS pro Mike McClure putting in his optimal NFL DFS lineup on Monday Night Football? Visit SportsLine now to see the full optimal tournament and cash game lineups for Monday night from a professional DFS player who has almost $2 million in career winnings, and find out.

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