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The Baltimore Ravens and Indianapolis Colts are set to square off in a key AFC battle on Monday Night Football. The Ravens enter Monday's clash averaging 420 yards per game on offense, while the Colts are averaging over 110 rushing yards per contest thus far this season. With a limited number of players to choose from in the NFL DFS player pool on Monday night, knowing which matchups to exploit could prove to be extremely lucrative. 

Should your Ravens vs. Colts NFL DFS strategy include rostering a player like Jonathan Taylor, who recorded 103 rushing yards and a touchdown last week? Or should you build your NFL DFS lineups around Carson Wentz, who threw for 228 yards and two touchdowns in his last outing? Before locking in any NFL DFS picks for Colts vs. Ravens, be sure to check out the NFL DFS advice, player rankings, stacks and top daily Fantasy football picks from SportsLine's Mike McClure.

McClure is a legendary professional DFS player with almost $2 million in career winnings. His methodology has led to enormous cashes on FanDuel and DraftKings. He took down two high-stakes tournaments on FanDuel in 2020 and recorded a pair top-10 finishes in tournaments with over 130,000 entrants on DraftKings. His lineups also finished inside the top 1 percent in more than a dozen other tournaments last season.

He uses a powerful prediction model that simulates every snap of NFL action, taking factors such as matchups, statistical trends and injuries into account. This allows him to find the best DFS values that he shares only with members at SportsLine.

Now, McClure has turned his attention to Colts vs. Ravens and locked in his top daily Fantasy football picks. You can only see them by heading to SportsLine.

Top NFL DFS picks for Ravens vs. Colts

One of McClure's top NFL DFS picks for Monday Night Football is Ravens quarterback Lamar Jackson. The 2019 NFL MVP is coming off the second-highest passing game of his career as he threw for 316 yards along with a touchdown last week.

Jackson's passing yards have actually increased each game this season, so he could be in line for a career-high on Monday Night Football. Also, it's not like his running ability has gone anywhere either as he's averaging nearly 70 rushing yards per game. Jacoby Brissett went 195 consecutive pass attempts without a TD before facing the Colts last week and he threw two touchdowns in the game, so it's easy to see why McClure is high on Baltimore's signal caller on Monday night. 

Part of McClure's optimal NFL DFS strategy also includes rostering Colts receiver Michael Pittman. The second-year wideout has ascended to Indy's No. 1 receiver while T.Y. Hilton (neck) has been sidelined. Pittman has performed admirably in the role with 23 catches for 279 yards, which projects to nearly 1,200 yards over a full season.

Pittman's best game of the season came against the Rams' elite defense when he posted 123 yards vs. Los Angeles in Week 2. He could similarly exploit Baltimore's thin secondary, which is already without corner Marcus Peters and could be without starting safety DeShon Elliott (quad) on Monday night. Game flow should also benefit Pittman as Indianapolis is expected to be trailing for much of the game, which will lead to more scoring opportunities.

How to set NFL DFS lineups for Colts vs. Ravens

McClure is also targeting an undervalued player who is set to explode for huge numbers on Monday night. This pick could be the difference between winning your tournaments and cash games or going home with nothing. You can only see who it is here.

So who is Mike McClure putting in his optimal NFL DFS lineups for Monday Night Football? Visit SportsLine now to see optimal NFL DFS picks, rankings, advice, and stacks, all from a daily Fantasy expert with nearly $2M in winnings, and find out.