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The Pittsburgh Steelers began their season with 11 consecutive victories and were 8-3 against the spread, but after suffering back-to-back losses and failing to cover the spread, they're hoping to stop the bleeding in Week 15. They'll face the Bengals on Monday Night Football, and Cincinnati has lost five games in a row while covering the spread just once during that span. That's why the Steelers are 14-point favorites in the latest Week 15 NFL odds from William Hill Sportsbook, but can the banged up Steelers get the job done after two letdowns in a row?

On Sunday, the Kansas City Chiefs will visit the New Orleans Saints. Patrick Mahomes and company are favored by three according to the current NFL spreads. And in a game featuring one of the largest NFL Vegas odds of the week, the Los Angeles Rams are favored by a whopping 17 points over the New York Jets. All of the Week 15 NFL lines are listed below, and SportsLine's advanced computer model has all the NFL betting advice and predictions you need to make the best Week 15 NFL picks now.

The SportsLine Projection Model simulates every NFL game 10,000 times and is up nearly $7,900 for $100 players on its top-rated NFL picks since its inception five-plus years ago.

It's a sizzling 22-11 on top-rated NFL picks this season, already returning over $800. The model enters Week 15 on an incredible 118-76 roll on top-rated NFL picks that dates back to the 2017 season. Additionally, the model also ranked in the Top 10 on NFLPickWatch in three of the past four years on straight-up NFL picks and beat more than 95 percent of CBS Sports office pool players three times during that span. Anyone who has followed it is way up.

Now, it has examined the latest Week 15 NFL odds and NFL betting lines from William Hill, simulated every snap, and its predictions are in. Head to SportsLine now to see them all.

Top NFL predictions for Week 15

One of the top Week 15 NFL picks the model recommends: Arizona covers as a 6.5-point home favorite against Philadelphia. A dominant 26-7 win last Sunday over the Giants snapped a three-game losing streak for the Cardinals and Kliff Kingsbury.

Against a top-10 defense, the Cardinals had strong balance with 390 yards of total offense fueled by 159 rushing yards. Wide receiver DeAndre Hopkins had nine catches for 136 yards in the victory, while the Cardinals recorded eight sacks while forcing three turnovers.

The model predicts that Hopkins will approach 100 yards once again and that Cardinals quarterback Kyler Murray will generate nearly 300 yards of total offense and multiple touchdowns. The Cardinals cover in well over 50 percent of simulations, while the under (49.5) hits nearly 60 percent of the time.

Another one of the top Week 15 NFL predictions from the model: The Indianapolis Colts (-7) cover at home against the Houston Texans. The Colts are 15-3 in their last 18 games against the Texans at Lucas Oil Stadium. Indianapolis has won four of the last five meetings between these AFC South rivals and the Colts covered as three-point favorites in the teams' first meeting this season. 

The line opened at Indianapolis -6.5, but has moved up half-a-point since then. The model is calling for Colts quarterback Philip Rivers to throw for over 280 yards and two scores, while wide receiver T.Y. Hilton racks up 75 receiving yards. Indianapolis covers the spread in well over 50 percent of simulations, while the under (51) hits 60 percent of the time.

How to make Week 15 NFL picks 

The model has also made the call on every other game on the Week 15 NFL schedule and identified a Super Bowl contender that goes down hard. You can only get every pick for every game here.

What NFL picks can you make with confidence in Week 15? And which Super Bowl contender goes down hard? Check out the latest NFL odds from William Hill below and then visit SportsLine to see which NFL teams are covering in more than 50 percent of simulations, all from the model that is up nearly $7,900 on its top-rated NFL picks

NFL odds, matchups for Week 15

Sunday, Dec. 20 

Houston Texans vs. Indianapolis Colts (-7, 51)

Latest Odds: Indianapolis Colts -7.5

Detroit Lions vs. Tennessee Titans (-9.5, 53.5)

Latest Odds: Tennessee Titans -9

Tampa Bay Buccaneers vs. Atlanta Falcons (+6.5, 49)

Latest Odds: Atlanta Falcons +6

New England Patriots vs. Miami Dolphins (-1.5, 41.5)

Latest Odds: Miami Dolphins +1

Seattle Seahawks vs. Washington Football Team (+6, 43.5)

Latest Odds: Washington Football Team +6

Chicago Bears vs. Minnesota Vikings (-3, 47)

Latest Odds: Minnesota Vikings -2.5

Jacksonville Jaguars vs. Baltimore Ravens (-13, 48)

Latest Odds: Baltimore Ravens -12.5

San Francisco 49ers vs. Dallas Cowboys (+3, 45)

Latest Odds: Dallas Cowboys +4

New York Jets vs. Los Angeles Rams (-17, 43.5)

Latest Odds: Los Angeles Rams -17

Philadelphia Eagles vs. Arizona Cardinals (-6.5, 49.5)

Latest Odds: Arizona Cardinals -6

Kansas City Chiefs vs. New Orleans Saints (+3, 52.5)

Latest Odds: New Orleans Saints +2.5

Cleveland Browns vs. New York Giants (+6.5, 44)

Latest Odds: New York Giants +6

Monday, Dec. 21

Pittsburgh Steelers vs. Cincinnati Bengals (+14, 40)

Latest Odds: Cincinnati Bengals +14.5