Championship Weekend of the 2021 NFL Playoffs will take place on Sunday. Patrick Mahomes cleared the league's concussion protocol and will now face Josh Allen in a matchup of dynamic young quarterbacks as the Chiefs host the Bills in the 2021 AFC Championship Game. Kansas City is a three-point favorite in the latest NFL odds from William Hill Sportsbook. Also on Sunday, two future Hall-of-Famers will go head-to-head when Aaron Rodgers and the Packers host Tom Brady and the Buccaneers at Lambeau Field in the 2021 NFC Championship Game.

Green Bay is a 3.5-point favorite in the latest NFL spreads after opening at -3. How should you construct your NFL bets on Sunday? If you're feeling truly bold, SportsLine's proven computer model is going huge, putting together a four-way parlay of NFL best bets that could return a massive 10-1 payout.

The model, which simulates every NFL game 10,000 times, is up almost $7,900 for $100 players on top-rated NFL picks since its inception five-plus years ago. It is a sizzling 24-14 on top-rated NFL picks this season, returning well over $800. The model also enters Championship Weekend of the 2021 NFL Playoffs on an incredible 120-78 run on top-rated NFL picks that dates back to the 2017 season.

Additionally, the model also ranked in the Top 10 on NFLPickWatch in three of the past four years on straight-up NFL picks and beat more than 95 percent of CBS Sports office pool players three times during that span. Anyone who has followed it is way up.

Now, it has examined the latest 2021 Championship Weekend NFL odds and NFL betting lines from William Hill, simulated every snap, and its predictions are in. If you parlay its picks, you could be looking at payout of 10-1. You can only see them here

Top NFL predictions for the Championship Round

One of the top Championship Round NFL picks the model recommends: Bills vs. Chiefs goes under the total of 54.5. Both offenses have disappointed lately, with Kansas City managing just 22 points in a win over the Browns last week and Buffalo putting up just 17 against Baltimore.

The Bills went 4-for-13 on third downs against the Ravens after ranking first in third-down conversion rate (49.7), while the Chiefs managed just 19 points from five trips inside the red-zone.

The Chiefs haven't topped 23 points in three consecutive games. The model predicts that Allen and Mahomes will both throw for fewer than 260 yards and combine for fewer than four touchdowns on average. That's a big reason why the under hits in nearly 60 percent of simulations.

How to make Championship Weekend NFL picks

The model has also made the call against the spread in both conference title games and has found huge value on one of the underdogs. You can only get every pick for every game here.

What are the top NFL picks for Championship Weekend? And which underdog do you need to jump all over? Visit SportsLine now to see the NFL best bets for Championship Weekend, all from the model that is up nearly $7,900 on its top-rated NFL picks, and find out.