The 12-game Sunday slate kicked off in London with the Jacksonville Jaguars trying to end a 20-game losing streak against the 1-4 Miami Dolphins. The Detroit Lions are on a nine-game slide and face the Cincinnati Bengals at home, while the Arizona Cardinals are looking to remain the league's only unbeaten team when they visit the Cleveland Browns. A matchup of AFC division leaders also is on tap, with the Baltimore Ravens hosting the Los Angeles Chargers. Which players should you back in your NFL prop bets, and which NFL player props are exploitable?

Ravens running back Latavius Murray has only eclipsed 40 yards once this season, but Caesars Sportsbook favors him to go Over 42.5 yards (-120) in its latest Week 6 NFL props. Each game offers plenty of NFL prop picks for NFL Week 6, and there is value to be found if you comb through them. Before you make any 2021 NFL Week 6 prop bets, you need to see the top NFL picks and predictions from NFL props expert Alex Selesnick.

Over the past two seasons, Selesnick (aka PropStarz) is up 119 units on NFL props and futures plays. For a $100 bettor, that's a $12,000 return. PropStarz specializes in NFL and NBA prop betting, where he implements a combination of research, statistical analysis and mathematical modeling. His background playing competitive poker, Scrabble and backgammon helped form the foundation of his sports betting approach. 

Through five weeks, PropStarz is an impressive 16-9 on his picks for SportsLine, and he cashed in easily last week when he said Cleveland's Nick Chubb would go Over 15.5 carries (-125) listed at Caesars Sportsbook. He also took the free money on Bears quarterback Justin Fields to go Under 19.5 completions (-125).

The props guru predicted that both the Browns and Bears would count heavily on the run, and that's exactly what happened. Chicago rushed for 143 yards, and Fields barely topped that number on attempts, going 12-of-20 in a 20-9 win against the Raiders. Chubb toted the ball 21 times for 161 yards in the Browns' 47-42 loss to the Chargers

Now, after poring over hundreds of available Week 6 NFL prop bets, PropStarz has found five more picks he loves. He's only his NFL player prop bet picks at SportsLine

Top 2021 Week 6 NFL prop picks

One Week 6 NFL prop bet PropStarz is all over this week: Patriots tight end Hunter Henry will go Over 3.5 receptions. Henry had 115 catches in his final two seasons with Los Angeles and comes in off his best performance of the season. He has been targeted 19 times over the past three games, and last week against the Texans, the 26-year-old had six catches for 75 yards and a TD.

Dallas' defense is vulnerable against short passes and has allowed 27 catches and 330 yards to tight ends this season. With the rookie calling the shots, the Patriots have been relying on those, with more than half of Jones' passes going to backs and tight ends. "It takes time for players to acclimate to New England's playbook, and Henry is looking more comfortable each week," PropStarz told SportsLine. "I expect him to continue serving as a safety valve for Mac Jones." 

How to make 2021 NFL Week 6 player prop bet picks

PropStarz has locked in four other Week 6 NFL prop picks, including surprising backup players who could get their chance to shine in Week 6. PropStarz has been on fire with his predictions, and you need to see these picks before locking in your own NFL prop bets. You can only see his NFL Week 6 player prop picks at SportsLine.

What are the five best 2021 Week 6 NFL prop bets you can make? And which players are a must-back? Visit SportsLine now to see the best NFL Week 6 prop bets, all from the expert up 119 units the past two years, and find out.