The Los Angeles Rams will look to keep the ball out of the hands of Aaron Rodgers and the Green Bay Packers when the teams meet on Saturday in the 2021 NFL Playoffs. Los Angeles (11-6), the sixth seed, has had success keeping the ball away from opponents, averaging 32 minutes of possession. The Rams have also racked up more first downs than their opponents in 26 of the past 38 regular-season games for a plus-160 margin. Rams wide receiver Cooper Kupp (knee) is inactive.

Kickoff from Lambeau Field is set for 4:35 p.m. ET. Green Bay is a seven-point favorite in the latest Rams vs. Packers odds from William Hill Sportsbook, while the over-under for total points scored is 45. Before making any Packers vs. Rams picks, see the latest NFL predictions and betting advice from SportsLine's proven model.

The model, which simulates every NFL game 10,000 times, is up almost $7,900 for $100 players on top-rated NFL picks since its inception five-plus years ago. It is a sizzling 24-14 on top-rated NFL picks this season, returning well over $800. The model also enters the Divisional Round of the 2021 NFL Playoffs on an incredible 120-78 run on top-rated NFL picks that dates back to the 2017 season.

The model ranked in the Top 10 on NFLPickWatch three of the past four years on straight-up NFL picks and beat more than 95 percent of CBS Sports office pool players three times during that span. Anyone who has followed it is way up. 

Now, the model has set its sights on Rams vs. Packers. You can head to SportsLine to see its picks. Now, here are the latest NFL odds and trends for Packers vs. Rams:

  • Rams vs. Packers spread: Packers -7
  • Rams vs. Packers over-under: 45 points
  • Rams vs. Packers money line: Rams +285, Packers -345
  • LA: RB Cam Akers is the only Rams rookie to ever rush for 100 yards in a postseason game
  • GB: Making its league-most 34th postseason appearance

Why the Packers can cover

Quarterback Aaron Rodgers has put the team on his back and they have been on a roll, winning six consecutive games to close out the regular season. Rodgers led the NFL with 48 TD passes, tied for the fifth-most in a single season in NFL history, and became the first quarterback with three seasons of 40 or more TD passes. He led the NFL with a 121.5 rating, the second-highest single-season mark in league history.

Running back Aaron Jones has also been a nightmare for opposing defenses. He has four total touchdowns in two career playoff games and is looking for his third postseason game in a row with two or more scores. Jones ranked seventh in the league with 1,459 yards from scrimmage, including a career-high 1,104 rushing and 355 receiving yards, and had 11 touchdowns.

Jones has 25 touchdowns, including 22 rushing, in 26 career home games. He is looking for his eighth home game in a row with 90 or more yards from scrimmage.

Why the Rams can cover

Defensive lineman Aaron Donald (ribs) has been a beast and is officially active. Donald tied for the second-most sacks in the league this season with 13.5. He leads the NFL with 85.5 sacks since 2014 and surpassed Hall of Famer Derrick Thomas (85) for third-most sacks by a player in his first seven seasons since 1982. He recorded his first two postseason sacks in the NFC Wild Card Game at Seattle last week.

Another force on defense is linebacker Leonard Floyd, who had a career-high 10.5 sacks in 2020. He had two sacks in the NFC Wild Card Game and will look for his third postseason game in a row with a sack. He has 7.5 sacks in eight career games against Green Bay.

How to make Rams vs. Packers picks

SportsLine's model is leaning under on the total, with the simulations showing the teams combining for 46 points. The model also says one side of the spread hits well over 50 percent of the time. You can only see which side to back here.

So who wins Packers vs. Rams in the 2021 NFL Playoffs? And which side of the spread cashes well over 50 percent of the time? Visit SportsLine now to find out which side of the Packers vs. Rams spread you need to jump on Saturday, all from the model on a 120-78 roll, and find out.