A pair of NFC title contenders will meet when the Green Bay Packers take on the Arizona Cardinals on Thursday Night Football. The Packers (6-1), who have reached the postseason the past two seasons and 10 of the past 12, lead the NFC North by 2.5 games over the second-place Minnesota Vikings. The Cardinals (7-0), who are looking to make the playoffs for the first time since 2015, have a one-game lead over the Los Angeles Rams in the NFC West. Arizona has won five of the past eight meetings with Green Bay, including two postseason matchups.

Kickoff from State Farm Stadium in Glendale, Arizona, is set for 8:20 p.m. ET. Arizona is a six-point favorite in the latest Cardinals vs. Packers odds from Caesars Sportsbook, while the over-under for total points scored is 50.5. Before making any Packers vs. Cardinals picks, be sure to see the NFL predictions from SportsLine's R.J. White.  

White, a CBS Sports fantasy and gambling editor, ended the 2020 season on an 80-59 run on all NFL picks, returning more than $1,400 during that span. He also enters Week 8 of the 2021 NFL season on a 38-22-1 roll on NFL picks.

It's no surprise, as White has cashed huge twice in the world's most prestigious football handicapping competition, the Las Vegas SuperContest. More importantly, White is an amazing 46-13-1 on his last 60 against the spread picks involving the Packers. Anyone who has followed him is way up.

Now, White has broken down Packers vs. Cardinals from every angle and just locked in his NFL expert picks. You can head to SportsLine to see White's picks. Here are the NFL odds and trends for Cardinals vs. Packers:  

  • Cardinals vs. Packers spread: Arizona -6
  • Cardinals vs. Packers over-under: 50.5 points
  • Cardinals vs. Packers s money line: Green Bay +230, Arizona -280
  • GB: Under has hit in Packers' last four games
  • ARI: Cardinals have covered five in a row
Featured Game | Arizona Cardinals vs. Green Bay Packers

Why the Cardinals can cover

Arizona has started 7-0 for the first time since 1974, when the team was based in St. Louis. A big reason has been the play of its defense, including linebacker Chandler Jones, who has played his best football in the national spotlight. Jones has eight sacks and 11 tackles for loss in eight career Thursday Night Football games.

He is also looking for his fourth game in a row on Thursday with a sack and ninth game in a row on TNF with a tackle for loss. He had a sack and two tackles for loss in the last meeting against Green Bay.

Why the Packers can cover

Green Bay's defense has played well for much of the season and is ranked sixth-best in the league in passing yards allowed at 210.6. Safety Adrian Amos had two pass breakups last week against Washington and has five or more tackles in 10 of his past 11 games. In seven games this season, he is second on the team in tackles with 47, including 39 solo. He has three pass breakups and one interception.

Also looking to step up his game is tight end Robert Tonyan. In seven games this season, he has 15 receptions for 155 yards (10.3 average) and two touchdowns. He has three explosive plays of 20 or more yards and has converted eight first downs. Tonyan had a season-high 63 receiving yards last week against Washington, including a touchdown.

How to make Cardinals vs. Packers picks

For Thursday Night Football, White is leaning over the point total, and he also has identified a critical X-factor that makes one side of the spread a must-back. He's sharing what it is, and which side to back, only at SportsLine.

So who wins Packers vs. Cardinals on Thursday Night Football? And what critical X-factor makes one side a must-back? Visit SportsLine now to see which side of the Packers vs. Cardinals spread you should be all over, all from the expert who is 46-13 on NFL picks involving Green Bay, and find out.