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It's do-or-die time in the NFL, with one final week at hand to secure a spot in the playoffs, or for some teams the only first-round bye in their conference. The Packers, Saints and Seahawks all have the chance to finish the year as the No. 1 seed in the NFC if things break their way, but six other teams in the conference are battling for three playoff spots, including three in the NFC East, which I've been told someone has to win. In the AFC, five teams are alive for four spots, with Indianapolis the team on the outside looking in heading into the final day of the season.

Each week, we'll collect all of the best picks and gambling content from CBSSports.com and SportsLine in one place, so you can get picks against the spread from our CBS Sports experts as well as additional feature content for each game, including plays from top SportsLine experts and the SportsLine Projection Model, best bets from our staff, survivor picks and more. 

Enjoy our run-through of Week 17, and good luck in your games! All times ET. All NFL odds via William Hill Sportsbook.

What picks can you make with confidence in Week 17? And which Super Bowl contender goes down hard? Visit SportsLine to see which NFL teams are winning more than 50 percent of simulations, all from the model that is up over $7,800 on its top-rated picks.

Dolphins at Bills

Time: Sunday, 1 p.m. ET (CBS), stream on CBS All Access 

"This is the hardest game of all to pick this week. For me it comes down to this: the Bills have been considering these final games like the postseason already. They're playing like the second-best team in the NFL -- not just the AFC. I don't see Buffalo slowing its momentum, and I believe Miami will need some help Sunday in order to get into the playoffs." -- Jonathan Jones on why he has the Bills beating the Dolphins

Jones is 161-78-1 with his straight up picks heading into the final week of the season. Check out all the NFL insider's Week 17 picks in his Friday column.


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Pete Prisco
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Jason La Canfora
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Will Brinson
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Jared Dubin
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Ryan Wilson
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John Breech
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Dave Richard
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Jamey Eisenberg
Dolphins at Bills (-1)

Steelers at Browns

Time: Sunday, 1 p.m. ET (CBS), stream on CBS All Access 

Pete Prisco: "I'm taking Mason Rudolph and the 10. You can't beat Mason Rudolph, are you kidding me? This is a revenge game! ... Look, he stinks. He's not good. But 10 points? The Browns shouldn't be laying 10 points to the Steelers, and I know some guys are gonna get held out of this (game), but this line ballooned way too much. I'm taking the Steelers." 

R.J. White: "If the Browns can lose to the Jets, they can lose to Pittsburgh's second string. I don't know that they're gonna lose this game, but that backdoor is going to be wide open. Cleveland's won once by double-digits since Week 4, and that was against Colt McCoy a few weeks ago. I think Mason Rudolph can keep it close, so I would lean that way too, but it's not a best bet for me." 

Kenny White: "All in agreement. It is a best bet for me, I just can't see how this game can be 10. It's been overinflated because of the fact that Cleveland must win and Ben Roethlisberger's not playing, but Ben hasn't been that great as of late as well. So I don't think it's that much of a dropoff -- I've got a 3.5-point dropoff to Mason Rudolph. Readjusted the game, and I thought Pittsburgh should've been favored if everybody was playing, so I don't know how it can be adjusted 12 points. I made the game (Browns) -4, I think that's about as high as you can make Cleveland."

That's from the Pick Six Podcast, where I join Pete Prisco, Kenny White and Will Brinson every Friday to break down all the games from a gambling perspective, give out best bets and put together a Pick Six Parlay, which has hit four times this season. Give it a listen below and subscribe for great NFL content in your feed daily.


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Pete Prisco
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Jason La Canfora
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Will Brinson
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Jared Dubin
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Ryan Wilson
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John Breech
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Dave Richard
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Jamey Eisenberg
Steelers at Browns (-10)

Ravens at Bengals

Time: Sunday, 1 p.m. ET (CBS), stream on CBS All Access 

"For the second time in three years, these two teams are meeting in Week 17 in a game the Ravens need to win to keep their playoffs hopes alive and I think we all remember what happened the last time the Ravens needed a Week 17 win against the Bengals ... That was the Bengals knocking the Ravens out of the 2017 playoffs and putting the Bills in. The 2017 Bengals were a monstrous underdog -- the Ravens were favored by eight -- but they still managed to pull off the win. This week, the Bengals are also a monstrous underdog, so the planets could be aligning for another upset (I mean, the planets did seriously just align, so I'm not ruling out this possibility). The Bengals are playing their best football of the season on defense and actually look competent on offense, which could be an issue for Baltimore. Although I'm an admitted Bengals homer, I'm not going to pick them to win here, but I do think it will be a lot closer than people think." -- John Breech on why he's taking the Bengals to cover

Breech is still taking the Ravens to win, and he's 13-2 picking their games straight up this year. You can see all his picks and final score predictions in his Tuesday column, and be sure to sign up for the Pick Six newsletter to get more Breech in your inbox all week long.   


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Pete Prisco
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Jason La Canfora
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Will Brinson
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Jared Dubin
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Ryan Wilson
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John Breech
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Dave Richard
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Jamey Eisenberg
Ravens (-13) at Bengals

Cowboys at Giants

Time: Sunday, 1 p.m. ET (Fox), stream on fuboTV (Try for free)   

"This prediction is twofold: The G-Men beat the Cowboys, and then the Eagles beat Washington later in the day to secure New York's title. Honestly, it might be the safest one of the bunch. Everyone's drooling all over Dallas again after Andy Dalton put up 37 on a backup-laden Eagles secondary, but New York's defense will be feistier. Better yet, doesn't Jason Garrett somehow finding a way to best Mike McCarthy with the season on the line just feel like destiny? As for the Eagles' end of things, it might not be pretty, but Jalen Hurts is better than both Alex Smith and Taylor Heinickie, and Doug Pederson just might be coaching for his job. Done deal." -- Cody Benjamin on why he's taking the Giants to come out of the NFC East on Sunday 

Benjamin delivered five bold predictions for the final Sunday of the regular season, and you can check them all out in his column from earlier this week.


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Pete Prisco
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Jason La Canfora
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Will Brinson
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Jared Dubin
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Ryan Wilson
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John Breech
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Dave Richard
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Jamey Eisenberg
Cowboys (-3) at Giants

Falcons at Buccaneers

Time: Sunday, 1 p.m. ET (Fox), stream on fuboTV (Try for free) 

"The Buccaneers have given up 27 passing touchdowns this season, which is the 11th most in the league. Meanwhile the Falcons defense has improved since coach Dan Quinn was fired after Week 5, giving up just 20.9 points over the last 10 games versus 32.2 over the first five. I think Atlanta keeps this game close against a Tampa Bay team that has bigger goals ahead." -- Hammerin' Hank Goldberg on why the Falcons are one of his best bets

A Vegas legend, Goldberg is 46-29 on his best bets over more than a full season. You can see which two other teams made his best bet parlay over at SportsLine.


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Pete Prisco
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Jason La Canfora
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Will Brinson
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Jared Dubin
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Ryan Wilson
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John Breech
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Dave Richard
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Jamey Eisenberg
Falcons at Bucs (-6.5)

Jets at Patriots

Time: Sunday, 1 p.m. ET (CBS), stream on CBS All Access

"One bright spot of Cam Newton's game in New England this season has been the damage he's done with his feet in the red zone. The veteran has 12 rushing touchdowns, which ties a franchise record for a quarterback. When the Patriots get into the red area, Newton is still much more likely to take it in himself rather than throw it, which makes this his most favorable prop. The only concern is that his exposure to this game may be limited if he's benched in the second half like last week." -- Tyler Sullivan, on why he likes the prop bet of "Cam Newton anytime touchdown (+110)" 

You can check out Tyler's complete Jets-Patriots betting preview here.


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Pete Prisco
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Jason La Canfora
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Will Brinson
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Jared Dubin
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Ryan Wilson
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John Breech
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Dave Richard
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Jamey Eisenberg
Jets at Patriots (-3)

Vikings at Lions

Time: Sunday, 1 p.m. ET (Fox), stream on fuboTV (Try for free)  

"The line wants us to believe: The Lions will score more than three touchdowns. The Vikings' defense isn't bad, but the implied point total of 23.75 for the Lions without Matthew Stafford (or with a banged-up Stafford) is pretty aggressive. Detroit's defense doesn't have a pass rush or even good cover corners. Each of the Lions' last seven losses were by seven-plus points. This should be a blowout for the Vikings." -- Dave Richard on why he likes the Vikings to roll 

A senior Fantasy writer, Richard is leading all CBS experts by at least five games on our leaderboard heading into the final week. You can see his thoughts on every spread as well as get some Fantasy advice in his start/sit column.


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Pete Prisco
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Jason La Canfora
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Will Brinson
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Jared Dubin
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Ryan Wilson
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John Breech
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Dave Richard
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Jamey Eisenberg
Vikings (-7) at Lions

Packers at Bears

Time: Sunday, 4:25 p.m. ET (Fox), stream on fuboTV (Try for free) 

"Listen, the Bears are having a resurgence right now. They've won three straight games and have scored 30 or more points in four straight games for the first time since like 1785. That's all well and good, but it's not like Mitch Trubisky has taken his game to another level. They've just played four bad teams! Now they're facing a Packers team hoping to secure a first-round bye with a win. Oh, and did you know that Rodgers isn't just content to beat the Bears on the field, but against the spread too? He's 17-7 ATS against them in his career. The next chapter of my nightmare starts on Sunday afternoon." -- Tom Fornelli on why the Packers are one of his best bets 

Fornelli is sitting exactly on .500 with his best bets for the season, so he's looking for one winning week to put him over the top. Check out all his best bets in his Thursday column.


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Pete Prisco
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Jason La Canfora
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Will Brinson
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Jared Dubin
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Ryan Wilson
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John Breech
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Dave Richard
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Jamey Eisenberg
Packers (-5.5) at Bears

Saints at Panthers

Time: Sunday, 4:25 p.m. ET (Fox), stream on fuboTV (Try for free) 

"Motivation is a key concern for teams with nothing to play for in Week 17, but I have no such worry about the Panthers. Matt Rhule has had this team playing hard for weeks, leading to close losses in Minnesota and Green Bay as well as against the Broncos at home, before upsetting Washington last week behind a strong performance by the improving defense. The Panthers came close to beating the Saints in their first meeting -- a game Michael Thomas also missed -- even though New Orleans was coming off its bye. The Saints offense should regress one week after running all over the Vikings, and that should open the door for Teddy Bridgewater and Co. to chase a signature win to end the year." -- R.J. White on why the Panthers are one of his best bets

I've cashed twice in the Las Vegas SuperContest, widely considered the toughest sports gambling competition in the world. I've also hit on over 57% of my picks over the past five years combined. You can see all five of my Week 17 NFL picks against the SuperContest lines by heading to SportsLine, and use promo code WHITE to sign up for $1 for your first month of access to all SportsLine's picks and analysis. 


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Pete Prisco
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Jason La Canfora
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Will Brinson
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Jared Dubin
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Ryan Wilson
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John Breech
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Dave Richard
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Jamey Eisenberg
Saints (-6.5) at Panthers

Seahawks at 49ers

Time: Sunday, 4:25 p.m. ET (Fox), stream on fuboTV (Try for free)  

"The Seahawks are still in the running for the top seed, so they are playing to win. The 49ers looked good last week in beating Arizona, and you know they would love to beat their rival. It will be close, but Seattle will find a way to win it late. It won't be easy." -- Pete Prisco on why he has the Seahawks winning by only one point 

Prisco made the 49ers with the points one of his best bets on the Pick Six Podcast, but you can see all his final score predictions in his Wednesday column.


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Pete Prisco
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Jason La Canfora
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Will Brinson
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Jared Dubin
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Ryan Wilson
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John Breech
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Dave Richard
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Jamey Eisenberg
Seahawks (-5.5) at 49ers

Cardinals at Rams

Time: Sunday, 4:25 p.m. ET (CBS), stream on CBS All Access    

"This game is a flat-out mess. The Rams are missing Jared Goff and will start John Wolford. The Cardinals will have Kyler Murray but it's pretty obvious he's not entirely healthy. I'm gonna side with the team not starting a guy without an NFL pass attempt in his career." -- Will Brinson on why he's taking the Cardinals as a best bet 

Brinson has best bets on several games, including some player props, and you can see them all in his Friday column.


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Pete Prisco
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Jason La Canfora
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Will Brinson
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Jared Dubin
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Ryan Wilson
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John Breech
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Dave Richard
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Jamey Eisenberg
Cardinals at Rams (-1)

Titans at Texans

Time: Sunday, 4:25 p.m. ET (CBS), stream on CBS All Access 

"This has all the makings of a Derrick Henry showcase. Houston is on a four-game losing streak and fresh off a Week 16 loss to the Bengals where they gave up 540 yards of total offense. The Texans have allowed backs to run for 138.8 yards per game on a 5.4 yards per carry clip, both the most in the NFL. Meanwhile, Henry leads the league with 118.5 rushing yards per game. The Titans, who can clinch the AFC South with a win, are under .500 ATS this season but are 6-1 SU as a touchdown favorite under Mike Vrabel. The Texans haven't shown much fight this season and with Henry having easy running lanes, he should be able to run Tennessee into the playoffs." -- Tyler Sullivan on why the Titans are one of his locks this week 

Sully is looking to finish the season strong after a rough week 16, and you can see his locks for the week and final score predictions for every game in his Wednesday column.


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Pete Prisco
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Jason La Canfora
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Will Brinson
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Jared Dubin
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Ryan Wilson
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John Breech
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Dave Richard
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Jamey Eisenberg
Titans (-7.5) at Texans

Jaguars at Colts

Time: Sunday, 4:25 p.m. ET (CBS), stream on CBS All Access  

"There are a couple of reasons I'm taking the Colts to cover this big spread: revenge, and necessity. For one, the Jaguars' lone win came in the season opener against the Colts. That's a very embarrassing mark for an Indy team hoping to make the postseason. To make matters worse, that loss is likely why the Colts will miss the playoffs this year. ... They would become just the third 11-win team in NFL history to miss the playoffs. All they can do is take care of business against the Jaguars and hope one of the other AFC playoff hopefuls loses, and I think the Colts take out their frustration on the team that handed them that first loss of the season." -- Jordan Dajani on why the Colts are one of his best bets 

Dajani has delivered an impressive 121-109-8 ATS record on all his picks this year, though he has struggled when it comes to his top picks. You can see his final score predictions for every game in his Thursday column.


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Pete Prisco
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Jason La Canfora
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Will Brinson
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Jared Dubin
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Ryan Wilson
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John Breech
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Dave Richard
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Jamey Eisenberg
Jaguars at Colts (-14)

Chargers at Chiefs

Time: Sunday, 4:25 p.m. ET (Fox), stream on fuboTV (Try for free) 

"Yes, I'm aware that Patrick Mahomes and several other key players are going to rest with Kansas City having nothing to play for. But to that I say, so what? This is still a coaching matchup of Andy Reid vs. Anthony Lynn, and if the Chargers haven't managed a double-digit win against anyone other than the Jaguars this year, what makes you think they'll get it done against Chiefs backups?" -- R.J. White on why the Chiefs are part of his Teaser of the Week 

After a strong start to the season, the Teaser of the Week is just barely .500 overall on the year, so I'm looking for one more win to get turn in a profitable teaser season. Check out the other team in my teaser and my full rankings in my Wednesday column.


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Pete Prisco
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Jason La Canfora
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Will Brinson
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Jared Dubin
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Ryan Wilson
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John Breech
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Dave Richard
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Jamey Eisenberg
Chargers (-3.5) at Chiefs

Raiders at Broncos

Time: Sunday, 4:25 p.m. ET (CBS), stream on CBS All Access  

"(Jerry) Jeudy was targeted a career-high 15 times last week against the Chargers, but caught just six of those targets for 61 yards. He should have been in line for a career game, but he suffered through several egregious drops. I predict he comes out motivated and has a better performance this Sunday." -- Jordan Dajani on why he's taking Jeudy Over 39.5 receiving yards as one of his best props in this game 

Dajani also likes the Over to hit in the game, noting that Raiders games are 11-3-1 to the Over all season. You can see the rest of his picks and props to know in his betting breakdown of the matchup.


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Pete Prisco
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Jason La Canfora
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Will Brinson
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Jared Dubin
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Ryan Wilson
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John Breech
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Dave Richard
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Jamey Eisenberg
Raiders (-2.5) at Broncos

Washington at Eagles

Time: Sunday, 8:20 p.m. ET (NBC), stream on fuboTV (Try for free)     

A national sportswriter whose work appears in the New York Times and Los Angeles Times, Mike Tierney entered the season as SportsLine's top NFL expert, posting a 282-222 record from 2016-19 on his NFL picks after a 66-44 run last season.

Tierney has also had a sharp eye when it comes to sizing up Washington games, where he's on an 18-8 run in his last 26 against-the-spread picks. He's leaning to the Over in this matchup, but you can check out his latest ATS pick in a Washington game over at SportsLine.


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Pete Prisco
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Jason La Canfora
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Will Brinson
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Jared Dubin
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Ryan Wilson
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John Breech
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Dave Richard
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Jamey Eisenberg
Washington (-1.5) at Eagles

Thanks for checking us out, and good luck with your picks!