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There are several NFL betting trends that should be of high interest to anyone making Week 4 NFL picks. The Chiefs are 9-0 in their last nine road games against the Chargers as Kansas City visits Los Angeles on Sunday. Kansas City is coming off a 22-17 victory over the Falcons and the Chiefs are 8-1 against their last nine games dating back to last season. The Chiefs are also 6-1 against the spread in their last seven games against AFC opponents, but should you include Kansas City in your Week 4 NFL betting picks?

According to the latest Week 4 NFL spreads, the Chiefs are eight-point favorites on the road. Other intriguing NFL matchups in the Week 4 NFL spreads include Vikings vs. Packers (-2.5), Eagles vs. Buccaneers (+1) and Bills vs. Ravens (-2.5) on Sunday Night Football. Before making NFL Week 4 picks or bets, you need to see the NFL against the spread picks from the sharp money gamblers and professional football bettors in Las Vegas.

Sharp money bettors are notorious in Las Vegas for finding value in point spreads and betting lines that casual bettors may not see. These professional bettors are respected by sportsbooks in Vegas and all around the world, and their betting action often causes bookmakers to change their lines. 

Jay Kornegay, EVP of the Westgate SuperBook in Las Vegas, joined SportsLine NFL expert Jimmie Kaylor to share who the Vegas sharps are backing in the Week 3 NFL odds. Kornegay is a longtime oddsmaker at the SuperBook, and has been a key player on the Vegas bookmaking scene for more than 25 years. He was inducted into the Sports Betting Hall of Fame Class of 2024.

Now that the sharps in Las Vegas have had a chance to digest the Week 3 NFL odds, they've start to lock in their picks for the Week 3 NFL schedule. You can only see them by heading to SportsLine.

Top Vegas NFL sharp money picks for Week 4

For Week 4, one of the Sharp Money plays the SuperBook has taken is the Detroit Lions (-3.5, 46.5) covering at home against the Seattle Seahawks on Monday Night Football. The Lions have been extremely tough to beat at home, winning five of their last six games at Ford Field. Detroit has excelled on the defensive side of the ball this season, giving up just 17.7 points per game. The Lions have been extremely stout against the run, giving up only 76.7 rushing yards per game, which ranks fourth in the NFL.

Offensively, the Lions are averaging 399.7 yards per game, which also ranks fourth in the league. David Montgomery and Jahmyr Gibbs form one of the most explosive rushing attacks with both players averaging at least 4.5 yards per carry. Montgomery has scored a rushing touchdown in all three games this season, while Gibbs has eclipsed 100 all-purpose yards in each of his last two outings. The Seahawks have a perfect 3-0 record, but their opponents have posted a combined 3-6 mark this season. See who else the NFL Vegas sharps are backing in Week 4 here.

How to get sharp money Vegas NFL ATS picks for Week 4

The Vegas sharps have also targeted two other NFL games and already locked in their against the spread picks, including on a team in desperate need of a win. You can only see who they are backing in Week 4 here

Which NFL teams are the sharp money bettors in Las Vegas backing in Week 4? And which desperate team is getting all the attention? Visit SportsLine now to see the top NFL picks and best bets from respected professional football bettors in Las Vegas, and find out.