Guy was released by Indianapolis.
Guy's release could be a sign that T.J. Green or Clayton Geathers are able to return from injury. However, it's still an odd move because the Colts' injury-depleted secondary is in need of depth.
Guy had one tackle despite playing 37 snaps in Sunday's loss at Denver.
Guy took over at safety after Clayton Geathers left with a foot injury. Guy could start at safety if Geathers and T.J. Green remain out.
Guy left Sunday's loss to Detroit in the fourth quarter due to a sprained left ankle, the Indianapolis Star reports.
Guy was pushed into playing significant snaps with the Colts suffering several injuries in the secondary. The Colts had six members of the secondary injured late in the game.
Guy suffered a Grade One hamstring injury in Sunday's loss to Houston.
Guy had two tackles in the loss. It's not clear if he'll be available for a special teams role again this week.
The Colts have signed Winston Guy and released Rob Ruggiero from the practice squad.
Guy had been with the Jaguars earlier this season, but was waived from the practice squad in late September. Ruggiero had not appeared in a game with the Colts this year.
The Jaguars promoted safety Craig Loston from the practice squad and waived safety Winston Guy.
The Jaguars have made two changes to their starting lineup on defense heading into Week 4 at San Diego, according to The Florida Times-Union.
Josh Evans has supplanted Winston Guy as the starting free safety, and J.T. Thomas takes over for LaRoy Reynolds as the starting outside linebacker.
Jaguars safety Winston Guy is dealing with cramping Week 3.
Guy is considered questionable to return. He came into the game probable due to an illness. He notched two tackles before leaving.
The Jaguars should have most of their probable players Week 3 against the Colts.
Alan Ball, Chris Clemons, Johnathan Cyprien, Toby Gerhart, Winston Guy Jr., Paul Posluszny, Cecil Shorts III and Mickey Shuler are all active and ready to go.
Injuries will prevent the following Jaguars from suiting up Thursday against Atlanta: PK Josh Scobee, DB Winston Guy, CB Alan Ball, S Craig Loston, OT Austin Pasztor and Josh Wells, G Zane Beadles, DL Sen'Derrick Marks , TE Clay Harbor.
Jaguars defensive back Winston Guy was forced out of Friday's preseason game in Detroit with a left ankle injury. He sustained the injury in the first quarter and was helped off the field. He will likely be evaluated so that the team can know the extent of the injury.
Jaguars defensive back Winston Guy had his best game of the season Thursday, in a 27-20 win over the Texans in Week 14. Guy racked up eight tackles to finish third on the team, and nearly matching his total for the season.
Guy entered the game with just nine tackles in the first 10 games of his career.
The Jaguars placed 12 players on their Friday injury report, but nine are probable for the game against the Browns on Sunday.
The offensive players so designated are linemen Will Rackley (illness) and Cameron Bradfield (bicep) and wide receiver Cecil Shorts (groin). Running back Justin Forsett (foot) is out.
The defensive probables are cornerback Will Blackmon (shoulder), defensive end Andre Branch (knee), safety Winston Guy (shoulder), linebackers J.T. Thomas (ankle) and Geno Hayes (knee) and tackle Roy Miller (shoulder).
Jaguars cornerback Dwayne Gratz (hip), safety Winston Guy (hamstring), defensive tackle Abry Jones (back), defensive tackle Roy Miller (shoulder), tight end Danny Noble (hamstring), linebacker Paul Posluszny (concussion), guard Will Rackley (concussion), wide receiver Kerry Taylor (toe) and linebacker Geno Hayes (knee) were all cleared to play Week 12 at Houston. Every player was listed as probable except Hayes, who was questionable.
Several defensive players in various stages of recovery are on the injury report released Friday by the Jaguars.
Listed as questionable for the Sunday game against the Texans are defensive back Will Blackmon (shoulder) and linebacker Geno Hayes (knee). Those deemed probable are defensive backs Dwayne Gratz (hip) and Winston Guy (hamstring), linebacker Paul Posluszny (concussion) and linemen Abry Jones (back) and Roy Miller (shoulder).
Among the offensive players on the report is tight end Danny Noble, who is probable with a hamstring problem.
The Jaguars listed several defensive players as probable to play in London for the Week 8 game against San Francisco on Sunday. All those players are active for the game.
Those players are as follows: Linebacker Russell Allen (ribs); defensive linemen Andre Branch (knee), Sen'Derrick Marks (knee/ankle), Roy Miller (shoulder) and Jeremy Mincey (concussion); and defensive backs Johnathan Cyprien (calf), Winston Guy (back) and Dwayne Gratz (ankle).
The Jaguars have made QB Blaine Gabbert, WR Mike Brown, S Winston Guy, CB Alan Ball, CB Dwayne Gratz, TE Marcedes Lewis and DT Abry Jones inactive for Week 3 against the Seahawks.
Maurice Jones-Drew, who was ruled questionable coming into the week, was declared active for the game.
Among the players listed as inactive for the Jaguars Week 1 vs. Kansas City were quarterback Ricky Stanzi, guard Jacques McClendon, tackle Cameron Bradfield, safety Winston Guy, defensive end Abry Jones and linebacker Chris McCoy.
The Seahawks officially finalized their 53-man roster Saturday by terminating the contracts of defensive tackle Clinton McDonald, fullback Michael Robinson, quarterback Brady Quinn and cornerback Antoine Winfield.
In addition, Seattle waived the following 18 players from the roster: wide receiver Phil Bates, defensive tackle Michael Brooks, defensive tackle Dewayne Cherrington, wide receiver Arceto Clark, tight end Darren Fells, defensive back Winston Guy, wide receiver Chris Harper, tight end Cooper Helfet, defensive tackle Jaye Howard, guard Rishaw Johnson, tight end Sean McGrath, defensive back Ron Parker, linebacker Ty Powell, guard Ryan Seymour, defensive back DeShawn Shead, defensive tackle Sealver Siliga, guard Jared Smith and wide receiver Bryan Walters.
The Seahawks activated defensive back Winston Guy from their one-week roster exemption on Monday and waived wide receiver Deon Butler. Guy was suspended four games by the NFL in November for violating the leagues policy on performance-enhancing substances.