57 A.J. Epenesa DE

Epenesa, who had to leave the team's Week 9 contest against the Cardinals with a concussion, was able to practice fully Wednesday.

Not that concussions can ever come at the right time, but the rookie from Iowa did get the advantage of the bye to work his way through the protocol and will likely not miss any game action. Epenesa continues to work as a rotational piece as he gets acclimated to the NFL, as he hasn't seen more than 35 percent of the defensive snaps in any game this season.

Epenesa was ruled out for the rest of Sunday's game versus the Cardinals after suffering a concussion.

Epenesa has entered the league's five-step concussion protocol. The Bills are on bye next week, so the rookie second-round pick has 14 days to get cleared for a Week 12 matchup against the Chargers.

Epenesa is being evaluated for a head injury during Sunday's game against the Cardinals.

The team is likely checking Epenesa for a concussion, and if that diagnosis is confirmed, the rookie second-rounder will be done for the day. Epenesa recorded one solo tackle before departing.

Epenesa has been made a game-day inactive for Sunday's game against the Jets.

This is a bit of a shocker considering the rookie out of Iowa was a second-rounder in April and was the team's top pick. But hey, this was a strange offseason and players received no preseason game experience, so the Bills will start the season with a more veteran look at defensive end, an area where they have plenty of depth.

Epenesa signed his four-year rookie contract with the Bills on Friday, Field Yates of ESPN reports.

The Bills now have their highest pick from the 2020 draft under contract. Epenesa was taken in the second round but was considered by some to be a first-round talent. He figures to be a fixture in Buffalo's defensive end rotation immediately.

The Bills selected Epenesa in the second round of the 2020 NFL Draft, 54th overall.

Epenesa had some first-round hype during the draft process but a poor showing at the combine hurt his stock. He had a 5.04 in the 40-yard dash and his three-cone drill is in the 25th percentile among defensive ends. That lines up with what he showed on tape, but Epenesa's calling card is his play strength. He collected double-digit sacks in each of his last two years at Iowa. Epenesa will need to develop his pass-rush rush skills in Buffalo to be a contributor as a rookie, but his power and frame (6-foot-5, 275 pounds with 34.5-inch arms) are a good foundation.