Lane (groin) has been downgraded to out for Sunday's game against the Giants, Gregg Bell of The News Tribune reports.
Lane has practiced just sparingly over the last three weeks and was initially listed as doubtful for the Week 7 tilt. His absence means Shaquill Griffin will receive the start at right cornerback again, while Justin Coleman will slide into the nickel spot.
This move has been in the works for awhile and at this point, Avril is apparently seriously considering retirement. The 31-year-old could be designated to return from IR after eight weeks, but that seems unlikely based on how things are trending at this time.
Lane was a full participant Thursday and Friday, although Friday was just a walk-through, but also had the bye week to recover so the doubtful tag is fairly surprising. Rookie Shaquill Griffin will be slated to start opposite Richard Sherman once again with Lane unlikely to play.
Friday's practice was only a walk-through, but Bennett was also a full participant Thursday so the questionable designation is a bit surprising. The 31-year-old is likely expected to play given his full practice participation, but Quinton Jefferson and Marcus Smith (ankle) would likely see an increased workload if he is forced to sit.
Coming out of a bye week, Prosise suffered a minor setback and was limited at Wednesday's practice. He seems to be on track to play for the first time since Week 3, but his inclusion on the final injury report suggests it isn't quite a lock. J.D. McKissic has done a nice job filling in as the passing-down back, creating some questions about the extent of Prosise's role upon returning.