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During its brief history, RB Leipzig never has had the experience of squaring off against Liverpool on a pitch. Luckily for the German squad, it will enter the first meeting between the two sides with all the momentum. RB Leipzig will carry a four-game winning streak into its match against Liverpool on Tuesday in the first leg of the UEFA Champions League Round of 16. RB Leipzig began its run with three consecutive shutouts before edging Augsburg 2-1 in German Bundesliga action on Friday. Liverpool, meanwhile, limps into Tuesday's contest, having lost three straight games. 

Kickoff from Puskas Arena in Budapest, Hungary is set for 3 p.m. ET. The latest RB Leipzig vs. Liverpool odds from William Hill Sportsbook list Liverpool as a +124 money line favorite, while the over-under for total goals scored is 2.5. Before locking in any Liverpool vs. RB Leipzig picks, be sure to see the UEFA Champions League predictions and betting advice from SportsLine's proprietary European soccer model.

Created by two Norwegians -- professional poker player and sports bettor Jonas Gjelstad, and economics and engineering expert Marius Norheim -- the model analyzes worldwide betting data and exploits market inefficiencies, helping its followers cash in. Since coming to SportsLine in 2019, the algorithm is up more than $8,900.

The model also made some strong calls in the final group stage of the Champions League, correctly predicting RB Leipzig (+150) defeating Manchester United, Sevilla (+135) knocking off Rennes and Liverpool playing to a draw (+275) with Midtjylland.

Now, the model has set its sights on RB Leipzig vs. Liverpool. You can visit SportsLine now to see the picks. Here are several odds and trends for Liverpool vs. RB Leipzig:

  • RB Leipzig vs. Liverpool spread: Liverpool -0.5
  • RB Leipzig vs. Liverpool over-under: 2.5 goals
  • RB Leipzig vs. Liverpool money line: Liverpool +124, RB Leipzig +195
  • RBL: RB Leipzig has posted a shutout in four of its last six matches
  • LIV: The Reds have allowed a total of three goals in their six Champions League games

Top Champions League predictions for RB Leipzig vs. Liverpool

The model is leaning over 2.5 goals in Tuesday's matchup between RB Leipzig and Liverpool. The Reds have struggled to score of late, registering only two goals in their last three matches - all losses. But they do possess the services of Mohamed Salah, who scored both of those tallies and tops Liverpool with 23 goals in 33 games. Meanwhile, the Reds have had problems keeping the ball out of the net, surrendering seven goals in their last two outings.

That figures to be a problem against RB Leipzig, which has produced nine goals over its last three contests. The team has had 16 different players score this season, with Yussuf Poulsen (nine) and Angelino (eight) leading the charge. These squads have had the same level of offensive potency in the UEFA Champions League, as RB Leipzig has scored 11 goals in six matches while Liverpool has recorded 10 in as many games, which is one of the reasons the model is leaning toward the over on Tuesday. 

How to make Champions League picks for RB Leipzig vs. Liverpool

The model has also locked in a strong money-line pick for Liverpool vs. RB Leipzig. You can get that pick at SportsLine.

So who wins Liverpool vs. RB Leipzig? And where does all the betting value lie? Visit SportsLine now to find out which side of the RB Leipzig vs. Liverpool money line has all the value, all from the proprietary European soccer model that's up more than $8,900.