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There are more soccer games available to Americans on TV and via stream than ever before, and this weekend is no different with domestic competitions providing endless hours of top-level talent. From leagues in the Western hemisphere like MLS, Liga MX, Argentina and Brazil's first divisions and more, to the most popular leagues on the globe found in Europe, here are the five games that you should watch and some honorable mentions:

All times Eastern

5. PSG vs. Lyon

Date: Sunday, Sept. 19 | Time: 2:45 p.m.
TV: beIN Sports | Live stream: fuboTV (Try for free)
Caesars Sportsbook Odds: PSG -295; Draw +440; Lyon +750

Why watch: Arguably the two most talented teams in France face off as the world waits for Lionel Messi's first goal for PSG. The Parisians somehow drew Club Brugge on Wednesday in the Champions League and have yet to look super sharp with the Argentine in the side. Here's their chance against a Lyon team that lost Memphis Depay to Barcelona.

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4. West Ham vs. Manchester United

Date: Sunday, Sept. 19 | Time: 9 a.m. 
TV: NBCSN | Live stream: fuboTV (Try for free)
Caesars Sportsbook Odds: West Ham +350; Draw +270; Man. United -126

Why watch: Fresh off of their encouraging performance in the Europa League, the Hammers welcome Cristiano Ronaldo and company to London Stadium just days after United's shock defeat in the Champions League to Young Boys. This is a battle of top-six contenders, though the Red Devils are looking to show they are much more than that, but first they'll have to get out of their own way.

3. Valencia vs. Real Madrid

Date: Sunday, Sept. 19 | Time: 3 p.m.
TV/Live stream: ESPN+
Caesars Sportsbook Odds: Valencia +280; Draw +275; Real Madrid -110

Why watch: Real Madrid are Real Madrid, and they are full of veteran and young talent that makes them clear contenders in La Liga, with Eduardo Camavinga already fitting in nicely. On the other side, you have a Valencia team looking to return to glory after their Copa del Rey victory in 2019 with Jose Bordalas quickly turning this team into a competitor despite limited additions to the squad. Los Blancos are the favorites, but Mestalla will be rocking.

2. Tottenham vs. Chelsea

Date: Sunday, Sept. 19 | Time: 11:30 a.m.
Live stream: Peacock
Caesars Sportsbook Odds: Tottenham +360; Draw +270; Chelsea -127

Why watch: There are some injury issues for Spurs, and they have less rest after having played in Europe on Thursday, while Chelsea are looking fierce with Romelu Lukaku leading the front line. Tottenham showed that at home anything is possible, beating Manchester City to start the season, but Nuno Espirito Santos' team will need to dig team to get something from this in what's the game of the weekend in the Premier League.

1. Juventus vs. Milan

Date: Sunday, Sept. 19 | Time: 2:45 p.m.
TV: CBS Sports Network | Live stream: Paramount+
Caesars Sportsbook Odds: Juventus +113; Draw +245; Milan +240

Why watch: Two giants of Italy square off on Sunday looking to prove they are the favorites to win the league. Juventus have struggled in Serie A to start the season but hope their midweek win over Malmo in the Champions League can be a springboard to better form, while Milan may have lost at Liverpool on Wednesday but showed they are never out if it. Will Zlatan Ibrahimovic be fit after missing the midweek match with an Achilles strain?

Honorable mentions

(All times U.S./Eastern)

Friday, Sept. 17: Three games to watch:  

  • Premier League: Newcastle vs. Leeds, 3 p.m. (NBCSN -- stream via fuboTV)
  • Serie A: Sassuolo vs. Torino, 2:45 p.m. (Paramount+)
  • MLS: Inter Miami vs. New York Red Bulls (FS1 -- stream via fuboTV)

Saturday, Sept. 18: Three games to watch:

  • Premier League: Wolverhampton vs. Brentford, 7:30 a.m. (NBCSN -- stream via fuboTV)
  • Serie A: Inter vs. Bologna, 12 p.m. (Paramount+)
  • Serie A: Genoa vs. Fiorentina, 9 a.m. (Paramount+)

Sunday, Sept. 19: Three games to watch:

  • Serie A: Lazio vs. Cagliari, 12 p.m. (Paramount+)
  • La Liga: Real Sociedad vs. Sevilla, 10:15 a.m. (ESPN+)
  • Argentina Liga Profesional: Huracan vs. Independiente, 5 p.m. (Paramount+)